LncRNA GAS5 positively regulates IL‐10 expression in patients with generalized myasthenia gravis
Sign Up to like & getrecommendations! Published in 2021 at "Brain and Behavior"
DOI: 10.1002/brb3.2457
Abstract: LncRNA growth arrest‐specific transcript 5 (GAS5) has been proven to be involved in autoimmune diseases. Rheumatoid arthritis is a type of autoimmune disease that may affect myasthenia gravis (MG) patients. However, its direct role in… read more here.
Keywords: myasthenia gravis; lncrna gas5; gas5; positively regulates ... See more keywords
Evaluation of prognostic usefulness of long noncoding RNA GAS5 and FAL1 in papillary thyroid carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28425
Abstract: Genetic studies on cancers have revealed that lncRNA‐GAS5 and lncRNA‐FAL1 are overexpressed in some cancerous cells. The aim of the present investigation was to evaluate the roles of lncRNA‐GAS5 and lncRNA‐FAL1 gene expression changes in… read more here.
Keywords: lncrna fal1; gas5; fal1; gas5 lncrna ... See more keywords
LncRNA GAS5 regulates the proliferation, migration, invasion and apoptosis of brain glioma cells through targeting GSTM3 expression. The effect of LncRNA GAS5 on glioma cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-019-03185-0
Abstract: IntroductionTo investigate the effects of lncRNA GAS5 on the proliferation, migration, invasion and apoptosis of brain glioma cells.MethodsThe expression levels of lncRNA GAS5 and GSTM3 in normal glial cells (HEB) and glioma cells (U251 and… read more here.
Keywords: proliferation migration; glioma; glioma cells; lncrna gas5 ... See more keywords
LncRNA GAS5 upregulates Smad4 to suppress the apoptosis of chondrocytes induced by lipopolysaccharide.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of gerontology and geriatrics"
DOI: 10.1016/j.archger.2021.104478
Abstract: BACKGROUND Osteoarthritis (OA) is closely correlated with inflammation. It has been reported that lncRNA GAS5 plays an important role in inflammation, indicating the potential involvement of GAS5 in OA. This study was carried out to… read more here.
Keywords: overexpression; mir 146a; apoptosis; gas5 ... See more keywords
lncRNA GAS5 suppresses rheumatoid arthritis by inhibiting miR-361-5p and increasing PDK4.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.10.040
Abstract: Rheumatoid arthritis (RA) is an inflammatory disease that causes hyperplasia of synovial tissue and cartilage destruction. This research was to investigate the effects of lncRNA GAS5/miR-361-5p/PDK4 on rheumatoid arthritis. By qRT-PCR, GAS5 and PDK4 were… read more here.
Keywords: lncrna gas5; pdk4; rheumatoid arthritis; mir 361 ... See more keywords
LncRNA-GAS5 and β-Catenin as Independent Predictors of Asymptomatic Organ Damage in Nondiabetic Hypertensive Patients
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07960
Abstract: Hypertension is a serious medical condition that can increase the risk of developing heart, brain, kidney, and other diseases. Many asymptomatic hypertension patients experience asymptomatic organ damage (AOD). The purpose of this study was to… read more here.
Keywords: hypertensive patients; gas5 catenin; asymptomatic organ; catenin ... See more keywords
LncRNA growth arrest specific transcript 5 inhibits the growth of pituitary neuroendocrine tumors via miR-27a-5p/cylindromatosis axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2062086
Abstract: ABSTRACT The long noncoding RNA growth arrest-specific transcript 5 (GAS5) has been reported to function as a suppressor in many cancers. However, the role and mechanism of lncRNA GAS5 in pituitary neuroendocrine tumors (PitNETs) remain… read more here.
Keywords: growth; cyld; expression; mir 27a ... See more keywords
Effects of LncRNA GAS5/miR-137 general anesthesia on cognitive function by TCF4 inflammatory bodies in patients undergoing lumbar spinal canal decompression
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031880
Abstract: Lumbar spinal stenosis is a common orthopedic disease in clinical practice at present. Postoperative cognitive dysfunction (POCD) refers to the phenomenon of impaired memory. However, whether long noncoding RNA (LncRNA) GAS5 contributes to the mechanism… read more here.
Keywords: spinal canal; undergoing lumbar; canal decompression; lumbar spinal ... See more keywords
lncRNA GAS5 Induces Cell Apoptosis in Acute Myeloid Leukemia by Targeting Nrf2
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DOI: 10.1155/2022/5178122
Abstract: Objective This study is aimed at investigating the molecular mechanism of lncRNA GAS5-induced cell apoptosis in acute myeloid leukemia (AML) by targeting Nrf2. Methods The RNA interfering technique was utilized to silence THP-1 in AML… read more here.
Keywords: gas5 nrf2; gas5; cell apoptosis; lncrna gas5 ... See more keywords
The Neuropeptide-Related HERC5/TAC1 Interactions May Be Associated with the Dysregulation of lncRNA GAS5 Expression in Gestational Diabetes Mellitus Exosomes
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/8075285
Abstract: Objective The goal of this work was to look at the expression and probable role of exosomal long noncoding RNA (lncRNA) GAS5 in gestational diabetes mellitus (GDM), as well as forecast the importance of its… read more here.
Keywords: neuropeptide related; herc5 tac1; expression; lncrna gas5 ... See more keywords
Block Copolymer Nanomicelle-Encapsulated Curcumin Attenuates Cerebral Ischemia Injury and Affects Stem Cell Marker Expression by Inhibiting lncRNA GAS5
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells International"
DOI: 10.1155/2023/9821500
Abstract: Stroke has become the most common cause of death among residents in China, among which ischemic stroke accounts for the vast majority reaching 70% to 80%. It is of great importance to actively investigate the… read more here.
Keywords: cell; curcumin; expression; cerebral ischemia ... See more keywords