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   Articles with "lncrna hotair" as a keyword



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Analysis of clinical important of LncRNA-HOTAIR gene variations and ovarian cancer susceptibility.

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recommendations! Published in 2020 at "Molecular biology reports"

DOI: 10.1007/s11033-020-05797-6

Abstract: LncRNAs are of functional long non-coding RNAs, which have been shown to be involved in critical pathways in cancer development. LncRNA-HOTAIR gene overexpression has been reported in several cancers. The aim of this study was… read more here.

Keywords: susceptibility; lncrna hotair; cancer; gene ... See more keywords
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LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-33722-2

Abstract: Long noncoding RNAs (lncRNAs) are emerging as major regulators of a variety of cell signaling processes. Many lncRNAs are expressed in immune cells and appear to play critical roles in the regulation of immune response.… read more here.

Keywords: cytokine expression; response; hotair; expression ... See more keywords
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LncRNA HOTAIR promotes renal interstitial fibrosis by regulating Notch1 pathway via the modulation of miR‐124

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recommendations! Published in 2019 at "Nephrology"

DOI: 10.1111/nep.13394

Abstract: To understand the mechanism of long non‐coding RNA (LncRNA) HOTAIR on renal interstitial fibrosis (RIF) by regulating Notch1 pathway via the modulation of miR‐124. read more here.

Keywords: interstitial fibrosis; notch1 pathway; pathway via; renal interstitial ... See more keywords
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POS0425 INCREASED KERATIN 9 EXPRESSION IN SYSTEMIC SCLEROSIS SKIN IS DRIVEN BY THE lncRNA HOTAIR FROM FIBROBLAST DERIVED EXOSOMES

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recommendations! Published in 2021 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2021-eular.2278

Abstract: Skin fibrosis is the hallmark fibrotic manifestation of systemic sclerosis (SSc). Despite a key role of tissue fibroblasts, skin changes extend to the keratinocyte layer, which contribute to the loss of skin function. RNA seq.… read more here.

Keywords: expression; systemic sclerosis; skin; lncrna hotair ... See more keywords
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lncRNA HOTAIR Inhibition by Regulating HMGB1/ROS/NF-κB Signal Pathway Promotes the Recovery of Spinal Cord Function

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recommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2022/4955982

Abstract: Spinal cord ischemia-reperfusion injury (SCII) is one of the most serious complications of clinical aortic aneurysm and vascular malformation surgery. Long noncoding RNA (lncRNA) is involved in the progression of SCII, whereas long noncoding RNA… read more here.

Keywords: hotair inhibition; lncrna hotair; hotair; spinal cord ... See more keywords
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LncRNA HOTAIR promotes proliferation, invasion and migration in NSCLC cells via the CCL22 signaling pathway

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recommendations! Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0263997

Abstract: Long noncoding RNA (LncRNA) is a new type of regulatory RNA. LncRNA HOX antisense intergenic RNA (HOTAIR), as an oncogene in non-small cell lung cancer (NSCLC), is one of the key determinants of tumor progression.… read more here.

Keywords: cell; lncrna hotair; ccl22; hotair ... See more keywords
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LncRNA HOTAIR as Prognostic Circulating Marker and Potential Therapeutic Target in Patients with Tumor Diseases.

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recommendations! Published in 2017 at "Current drug targets"

DOI: 10.2174/1389450117666151209122950

Abstract: In the recent years the importance of the role played by non-coding RNA on the regulation of gene expression was increased by numerous studies. The research mainly focused on small ncRNAs, such as miRNAs, while… read more here.

Keywords: prognostic circulating; hotair prognostic; circulating marker; lncrna hotair ... See more keywords

LncRNA HOTAIR regulates cell invasion and migration in endometriosis through miR-519b-3p/PRRG4 pathway

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.953055

Abstract: Endometriosis is a common benign disease in gynecology and has malignant biological behaviors, such as hyperplasia, invasion, metastasis, and recurrence. However, the pathogenesis of endometriosis remains unclear. The present study aimed to investigate whether LncRNA… read more here.

Keywords: mir 519b; invasion migration; invasion; lncrna hotair ... See more keywords

Inhibitory effect of calycosin on breast cancer cell progression through downregulating lncRNA HOTAIR and downstream targets: HuR and IGF2BP1

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recommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"

DOI: 10.3724/abbs.2022197

Abstract: Breast cancer is the most commonly diagnosed cancer worldwide. Previously, we reported that calycosin, a typical isoflavone phytoestrogen, triggers apoptosis and is associated with lncRNA HOTAIR in the estrogen receptor (ER)-positive breast cancer MCF-7-cell line.… read more here.

Keywords: breast cancer; hotair; hur igf2bp1; lncrna hotair ... See more keywords