The role of lncRNA MALAT1 in cardiovascular disease
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DOI: 10.1002/iub.2210
Abstract: Cardiovascular disease (CVD) is the first leading cause of death worldwide. Understanding the molecular mechanism of signaling pathways involved in pathology of CVD is benefit for targeted therapeutics. Recently, long non‐coding RNAs (lncRNAs) are found… read more here.
Keywords: pathology; lncrna malat1; malat1 cardiovascular; cardiovascular disease ... See more keywords
Downregulation of lncRNA MALAT1 contributes to renal functional improvement after duodenal-jejunal bypass in a diabetic rat model
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DOI: 10.1007/s13105-018-0636-y
Abstract: Ameliorated renal function has been reported after bariatric surgery, but the mechanisms underlying this phenomenon are not well-studied. To investigate whether the long non-coding RNA (lncRNA) MALAT1 mediates the amelioration of diabetic nephropathy after duodenal-jejunal… read more here.
Keywords: surgery; malat1; duodenal jejunal; lncrna malat1 ... See more keywords
LncRNA MALAT1 aggravates the retinal angiogenesis via miR-320a/HIF-1α axis in diabetic retinopathy.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental eye research"
DOI: 10.1016/j.exer.2022.108984
Abstract: Diabetic retinopathy (DR) is one of the most serious microvascular complications of diabetes and an important cause of blindness in adults. In previous study, we found that miR-320a alleviated the damage of muller cells in… read more here.
Keywords: hif; angiogenesis; mir 320a; lncrna malat1 ... See more keywords
MicroRNA-mediated silence of onco-lncRNA MALAT1 in different ESCC cells via ligand-functionalized hydroxyl-rich nanovectors.
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DOI: 10.1039/c6nr09668a
Abstract: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies worldwide. Long noncoding RNA (lncRNA) MALAT1 acts as an essential oncogene lncRNA (onco-lncRNA) in the development of ESCC. Down-regulation of onco-lncRNA MALAT1 mediated… read more here.
Keywords: different escc; lncrna malat1; escc; malat1 different ... See more keywords
Retracted Article: LncRNA MALAT1 aggravates MPP-induced neuronal injury by regulating miR-212 in SH-SY5Y cells
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c8ra09260e
Abstract: Parkinson's disease (PD) is the most common neurodegenerative disease and its incidence is rising. read more here.
Keywords: aggravates mpp; retracted article; mpp induced; article lncrna ... See more keywords
LncRNA MALAT1-deficiency restrains lipopolysaccharide (LPS)-induced pyroptotic cell death and inflammation in HK-2 cells by releasing microRNA-135b-5p
Sign Up to like & getrecommendations! Published in 2021 at "Renal Failure"
DOI: 10.1080/0886022x.2021.1974037
Abstract: Abstract Long non-coding RNAs (LncRNAs) participate in the regulation of chronic kidney disease (CKD), and acute kidney injury (AKI) is identified as an important risk factor for CKD. This study investigated the involvement of a… read more here.
Keywords: lps induced; lncrna malat1; mirna 135b; cell ... See more keywords
Long non‐coding RNA MALAT1 mediates hypoxia‐induced pro‐survival autophagy of endometrial stromal cells in endometriosis
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DOI: 10.1111/jcmm.13947
Abstract: Endometriosis is a common gynecological disease characterized by diminished apoptosis, sustained ectopic survival of dysfunctional endometrial cells. Hypoxia has been implicated as a crucial microenvironmental factor that contributes to endometriosis. It has been reported that… read more here.
Keywords: stromal cells; endometrial stromal; malat1; lncrna malat1 ... See more keywords
lncRNA MALAT1 participates in metformin inhibiting the proliferation of breast cancer cell
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16742
Abstract: In recent years, the repurposing of conventional and chemotherapeutic drugs is recognized as an alternative strategy for health care. The main purpose of this study is to strengthen the application of non‐oncological drug metformin on… read more here.
Keywords: treatment; metformin; breast cancer; lncrna malat1 ... See more keywords
Mechanism of METTL14 and m6A modification of lncRNA MALAT1 in the proliferation of oral squamous cell carcinoma cells.
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DOI: 10.1111/odi.14220
Abstract: OBJECTIVES Methyltransferase-like 14 (METTL14) plays an epigenetic role in various cancer through N6-methyladenosine (m6A) modification. This study sought to analyze the mechanism of METTL14 in oral squamous cell carcinoma (OSCC) cell proliferation. METHODS Expression levels… read more here.
Keywords: lncrna malat1; cell; m6a modification; mir 224 ... See more keywords
PO-357 miR-145–5 p, miR-196a-5p, miR-222–3 p and lncRNA MALAT1 as non-invasive markers in advanced laryngeal squamous cell carcinoma
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DOI: 10.1136/esmoopen-2018-eacr25.869
Abstract: Introduction Non-coding RNAs are become one of the most investigated biomarkers in non-invasive diagnostics of cancer diseases. In this study we explore the potential of three miRNAs and one lncRNA as biomarkers in advanced laryngeal… read more here.
Keywords: mir 145; mir; mir 196a; malat1 ... See more keywords
The lncRNA MALAT1 is upregulated in urine of type 1 diabetes mellitus patients with diabetic kidney disease
Sign Up to like & getrecommendations! Published in 2023 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2022-0291
Abstract: Abstract Long non-coding RNAs (lncRNAs) are RNAs with >200 nucleotides that are unable to encode proteins and are involved in gene expression regulation. LncRNAs have a key role in many physiological and pathological processes and,… read more here.
Keywords: lncrna malat1; t1dm patients; malat1 upregulated; type diabetes ... See more keywords