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   Articles with "lncrna meg3" as a keyword



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LncRNA MEG3 ameliorates NiO nanoparticles‐induced pulmonary inflammatory damage via suppressing the p38 mitogen activated protein kinases pathway

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recommendations! Published in 2022 at "Environmental Toxicology"

DOI: 10.1002/tox.23464

Abstract: The lung inflammatory damage could result from the nickel oxide nanoparticles (NiO NPs), in which the underlying mechanism is still unclear. This article explored the roles of long noncoding RNA maternally expressed gene 3 (lncRNA… read more here.

Keywords: inflammatory damage; nio nps; lncrna meg3; mapk pathway ... See more keywords
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LncRNA-MEG3 Regulates the Inflammatory Responses and Apoptosis in Porcine Alveolar Macrophages Infected with Haemophilus parasuis Through Modulating the miR-210/TLR4 Axis.

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recommendations! Published in 2021 at "Current microbiology"

DOI: 10.1007/s00284-021-02590-x

Abstract: Haemophilus parasuis (H. parasuis, HPS) can elicit serious inflammatory responses and cause enormous economic loss to swine industry worldwide. However, the factors responsible for systemic infection and inflammatory responses of HPS have not yet been… read more here.

Keywords: responses apoptosis; inflammatory responses; meg3; lncrna meg3 ... See more keywords
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Down-regulated lncRNA MEG3 promotes osteogenic differentiation of human dental follicle stem cells by epigenetically regulating Wnt pathway.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.07.160

Abstract: Our previous long noncoding RNA (lncRNA) microarray results showed that lncRNA MEG3 (maternally expressed 3) was significantly downregulated in human dental follicle cells than human periodontal ligament cells. Latest studies show that MEG3 contributes to… read more here.

Keywords: follicle stem; lncrna meg3; wnt; dental follicle ... See more keywords
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LncRNA MEG3 reverses CCl4-induced liver fibrosis by targeting NLRC5.

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recommendations! Published in 2021 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2021.174462

Abstract: Liver fibrosis is a persistent pathological repair of chronic liver injury, which is characterized by excessive deposition of collagen-dominated extracellular matrix (ECM). It is well known that hepatic fibrosis can be reversed in the absence… read more here.

Keywords: targeting nlrc5; meg3; fibrosis; lncrna meg3 ... See more keywords
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Cyclophosphamide promotes the proliferation inhibition of mouse ovarian granulosa cells and premature ovarian failure by activating the lncRNA-Meg3-p53-p66Shc pathway.

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recommendations! Published in 2017 at "Gene"

DOI: 10.1016/j.gene.2016.10.011

Abstract: The dysfunction of ovarian granulosa cells (OGCs) directly affects the premature ovarian failure (POF). In vivo experiments showed that cyclophosphamide significantly induced mouse ovarian atrophy and proliferation inhibition of OGCs. The expressions of p53, p66Shc… read more here.

Keywords: lncrna meg3; p53 p66shc; group; cyclophosphamide ... See more keywords
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lncRNA MEG3 Inhibits the Proliferation and Growth of Glioma Cells by Downregulating Bcl-xL in the PI3K/Akt/NF-κB Signal Pathway

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recommendations! Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/3729069

Abstract: This study was conducted to investigate the impact and mechanisms of lncRNA MEG3 on glioma cells. lncRNA MEG3 was lowly expressed in glioma cells as compared to noncancer cells. Overexpression of MEG3 significantly downregulated the… read more here.

Keywords: downregulating bcl; pi3k akt; akt signal; lncrna meg3 ... See more keywords
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LncRNA MEG3-TRPV1 signaling regulates chronic inflammatory pain in rats

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recommendations! Published in 2022 at "Molecular Pain"

DOI: 10.1177/17448069221144246

Abstract: Osteoarthritis (OA) is a common osteoarthropathy with chronic inflammatory pain as the core symptom in middle-aged and elderly people. LncRNA MEG3 (Maternally expressed gene 3) is involved in the development of OA via regulation of… read more here.

Keywords: lncrna meg3; inflammatory pain; pain; trpv1 ... See more keywords
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LncRNA MEG3 expression in sepsis and its effect on LPS-induced macrophage function.

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recommendations! Published in 2020 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2020.66.5.23

Abstract: Sepsis is a dangerous disease that is caused by an overreaction of the body's immune system to infection and gradually spreads throughout the body. This experiment was carried out to explore the expression of LncRNA… read more here.

Keywords: sepsis; lncrna meg3; lps induced; group ... See more keywords
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Propofol rescued astrocytes from LPS-induced inflammatory response via blocking LncRNA-MEG3/NF-κB axis.

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recommendations! Published in 2022 at "Current neurovascular research"

DOI: 10.2174/1567202619666220316112509

Abstract: OBJECTIVE Evidences had demonstrated that propofol attenuated neuro-inflammation following brain ischemia. Moreover, LncRNA-MEG3 was identified as an independent prognostic marker for ischemic stroke patients, and was found to be correlated with cerebral ischemia in animal… read more here.

Keywords: astrocytes lps; lncrna meg3; propofol; meg3 axis ... See more keywords
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Diagnostic value of LncRNA-MEG3 as a serum biomarker in patients with hepatitis B complicated with liver fibrosis.

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recommendations! Published in 2019 at "European Review for Medical and Pharmacological Sciences"

DOI: 10.26355/eurrev_201905_17943

Abstract: OBJECTIVE: The aim of this work was to explore whether lncRNA-MEG3 could serve as a serum biomarker for diagnosing chronic hepatitis B (CHB) and improve the early diagnostic and treatment efficacies. PATIENTS AND METHODS: Serum… read more here.

Keywords: serum level; lncrna meg3; level lncrna; meg3 ... See more keywords
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LncRNA MEG3 inhibits proliferation and promotes apoptosis of osteosarcoma cells through regulating Notch signaling pathway.

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recommendations! Published in 2020 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202001_20034

Abstract: OBJECTIVE To explore the effect of long non-coding ribonucleic acid (lncRNA)-maternally expressed gene 3 (MEG3) on the Notch signaling pathway, and its influences on the proliferation and apoptosis of osteosarcoma MG-63 cells. MATERIALS AND METHODS… read more here.

Keywords: group; lncrna meg3; osteosarcoma cells; proliferation ... See more keywords