Analysis of lncRNA–mRNA networks after MEK1/2 inhibition based on WGCNA in pancreatic ductal adenocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29255
Abstract: Pancreatic ductal adenocarcinoma (PDA) responds poorly to treatment. Efforts have been exerted to prolong the survival time of PDA, but the 5‐year survival rates remain disappointing. Understanding the molecular mechanisms of PDA development is significant.… read more here.
Keywords: analysis; lncrna mrna; mrna networks; pancreatic ductal ... See more keywords
Dissection of functional lncRNAs in Alzheimer's disease by construction and analysis of lncRNA-mRNA networks based on competitive endogenous RNAs.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.11.143
Abstract: Alzheimer's disease (AD) is a neurodegenerative disorder that is the most common cause of dementia in the elderly, and intracellular neurofibrillary tangles (NFTs) are one of the pathological features of AD. Recent studies have suggested… read more here.
Keywords: alzheimer disease; analysis; endogenous rnas; lncrna mrna ... See more keywords
Hypoxic preconditioning enhances cell hypoxia tolerance and correlated lncRNA and mRNA analysis
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.07.014
Abstract: Aims: Hypoxia makes cells death but it is not always true. Short term anoxia can boost remaining cells activities and promote tissue repair. This study is to explore the effects of hypoxic preconditioning (HP) on… read more here.
Keywords: group; hypoxic preconditioning; lncrna mrna; culture medium ... See more keywords
Comprehensive lncRNA and mRNA profiles in peripheral blood mononuclear cells derived from ankylosing spondylitis patients by RNA-sequencing analysis
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000027477
Abstract: Supplemental Digital Content is available in the text Abstract The present study aimed to investigate the comprehensive expression profiles of long non-coding RNA (lncRNA) in ankylosing spondylitis (AS). The peripheral blood samples were collected from… read more here.
Keywords: blood mononuclear; peripheral blood; expression profiles; ankylosing spondylitis ... See more keywords
Transcriptome sequencing reveals a lncRNA–mRNA interaction network in extramammary Paget’s disease
Sign Up to like & getrecommendations! Published in 2021 at "BMC Medical Genomics"
DOI: 10.1186/s12920-021-01135-2
Abstract: Background Extramammary Paget’s disease (EMPD) is a rare malignant intraepidermal adenocarcinoma that is poorly understood. Regulatory long noncoding RNAs (lncRNAs) are characterized in many species and shown to be involved in processes such as development… read more here.
Keywords: interaction network; lncrna mrna; network; extramammary paget ... See more keywords
Berberine ameliorates vascular dysfunction by a global modulation of lncRNA and mRNA expression profiles in hypertensive mouse aortae
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0247621
Abstract: Objective The current study investigated the mechanism underlying the therapeutic effects of berberine in the vasculature in hypertension. Methods Angiotensin II (Ang II)-loaded osmotic pumps were implanted in C57BL/6J mice with or without berberine administration.… read more here.
Keywords: expression profiles; lncrna mrna; expression; mrna expression ... See more keywords
Investigation of lncRNA-mRNA co-expression network in ETV6-RUNX1-positive pediatric B-cell acute lymphoblastic leukemia
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0253012
Abstract: ETV6/RUNX1 gene fusion is the most common chromosomal translocation abnormality occurred in pediatric B-cell acute lymphoblastic leukemia (B-ALL). Compared with ETV6-RUNX1-negative patients, ETV6-RUNX1-positive patients possess more improved treatment strategies but higher risk to relapse. In… read more here.
Keywords: etv6 runx1; runx1 positive; lncrna mrna; expression ... See more keywords
Identification of Lncrna-Mrna Networks in Hepg2 Cells upon ATP7B Knockout and Copper Accumulation
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v52i5.12720
Abstract: Background: Hepatolenticular degeneration (HLD) is an inherited disorder caused by the mutation in the adenosine triphosphatase copper transporting β gene (ATP7B). W aimed to explore the genetic changes in HLD using bioinformatics analysis. Methods: The… read more here.
Keywords: copper; atp7b; knockout copper; atp7b knockout ... See more keywords
A study of the differential expression profiles of Keshan disease lncRNA/mRNA genes based on RNA-seq.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular diagnosis and therapy"
DOI: 10.21037/cdt-20-746
Abstract: Background This study aims to analyze the differential expression profiles of lncRNA in Keshan disease (KSD) and to explore the molecular mechanism of the disease occurrence and development. Methods RNA-seq technology was used to construct… read more here.
Keywords: expression; differential expression; expression profiles; lncrna mrna ... See more keywords
Genetic Basis of Sexual Maturation Heterosis: Insights From Ovary lncRNA and mRNA Repertoire in Chicken
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.951534
Abstract: Sexual maturation is fundamental to the reproduction and production performance, heterosis of which has been widely used in animal crossbreeding. However, the underlying mechanism have long remained elusive, despite its profound biological and agricultural significance.… read more here.
Keywords: signaling pathway; heterosis; lncrna mrna; maturation heterosis ... See more keywords
Construction of a ceRNA-based lncRNA–mRNA network to identify functional lncRNAs in premature ovarian insufficiency
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.956805
Abstract: Premature ovarian insufficiency, characterized by ovarian infertility and low fertility, has become a significant problem in developed countries due to its propensity for late delivery. It has been described that the vital role of lncRNA… read more here.
Keywords: based lncrna; premature ovarian; ovarian insufficiency; lncrna mrna ... See more keywords