LncRNA NEAT1 correlates with Th17 cells and proinflammatory cytokines, also reflects stenosis degree and cholesterol level in coronary heart disease patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23975
Abstract: Long non‐coding RNA nuclear enriched abundant transcript 1 (lnc‐NEAT1) regulates endothelial cell functions, CD4+ T cell regulation and chronic inflammation related to coronary heart disease (CHD). Then this case‐control study measured lnc‐NEAT1 expression in CHD… read more here.
Keywords: coronary heart; neat1 correlates; lncrna neat1; heart disease ... See more keywords
LncRNA NEAT1 Regulates Infantile Pneumonia by Sponging miR-146b
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Biotechnology"
DOI: 10.1007/s12033-021-00331-w
Abstract: This study designed to investigate the potential role of lncRNA NEAT1/miR-146b in infantile pneumonia. In this study, 58 children with pneumonia and 58 healthy children collected for routine examination from December 2016 to January 2019.… read more here.
Keywords: neat1 regulates; mir 146b; infantile pneumonia; lncrna neat1 ... See more keywords
LncRNA Neat1 positively regulates MAPK signaling and is involved in the pathogenesis of Sjögren's syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106992
Abstract: OBJECTIVE Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands. Recent, studies have shown that the long noncoding RNA (lncRNA) NEAT1 plays a crucial role in regulating… read more here.
Keywords: expression; pma ionomycin; pathogenesis; lncrna neat1 ... See more keywords
Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.06.019
Abstract: Despite the prominent role of TDP-43 in neurodegeneration, its physiological and pathological functions are not fully understood. Here, we report an unexpected role of TDP-43 in the formation of dynamic, reversible, liquid droplet-like nuclear bodies… read more here.
Keywords: phase separation; liquid phase; stress; lncrna neat1 ... See more keywords
Knockdown lncRNA NEAT1 regulates the activation of microglia and reduces AKT signaling and neuronal apoptosis after cerebral ischemic reperfusion
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71411-1
Abstract: Acute cerebral ischaemia may lead to serious consequences, including brain injury caused by uncontrolled reperfusion, which occurs when circulation is re-established. The long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) plays an important… read more here.
Keywords: knockdown lncrna; apoptosis; neat1; reperfusion ... See more keywords
LncRNA NEAT1 affects endometrial receptivity by regulating HOXA10 promoter activity
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2075198
Abstract: ABSTRACT In vitro fertilization and embryo transfer (IVF-ET) is one of the effective methods to treat female infertility. Poor endometrial receptivity (ER) is an important factor leading to embryo implantation dysfunction, which can reduce pregnancy… read more here.
Keywords: lncrna neat1; hoxa10 promoter; ctcf; embryo implantation ... See more keywords
Serum exosomal long noncoding RNA nuclear-enriched abundant transcript 1 predicts 90-day mortality in acute-on-chronic hepatitis B liver failure
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2021.1933442
Abstract: ABSTRACT Objectives: Acute-on-chronic hepatitis B liver failure (ACHBLF) is characterized by high short-term mortality, calling for accurate prognostic biomarkers. This study aims to evaluate the predictive value of serum exosomal long noncoding RNA nuclear-enriched abundant… read more here.
Keywords: acute chronic; serum exosomal; lncrna neat1; mortality ... See more keywords
Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/7630698
Abstract: Background Hepatoblastoma (HB) is the most common malignant tumor of the liver. MMP9 plays an essential role in HB. The purpose of our study was to screen for differentially expressed lncRNAs and miRNAs that targeted… read more here.
Keywords: derived exosomal; mir 132; 132 mmp9; lncrna neat1 ... See more keywords
LncRNA NEAT1 Targets miR-342-3p/CUL4B to Inhibit the Proliferation of Cutaneous Squamous Cell Carcinoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/8145129
Abstract: Objective This study investigated whether lncRNA NEAT1 could inhibit the proliferation of cutaneous squamous cell carcinoma (CSCC) cells by targeting miR-342-3p/CUL4B, thereby affecting the occurrence and development of CSCC. Methods Fluorescence quantitative PCR was used… read more here.
Keywords: cell; lncrna neat1; proliferation; cscc ... See more keywords
Melatonin Regulates lncRNA NEAT1/miR-138-5p/HIF-1α Axis through MOV10 to Affect Acid-Related Esophageal Epithelial Cell Pyroptosis.
Sign Up to like & getrecommendations! Published in 2023 at "Pharmacology"
DOI: 10.1159/000530090
Abstract: INTRODUCTION Acid-related inflammatory damage to the esophageal epithelium is a key component in the development of gastroesophageal reflux disease. Melatonin (MT) is considered as a potential therapeutic agent, but its molecular mechanism is unknown. METHODS… read more here.
Keywords: acid related; lncrna neat1; mov10; mir 138 ... See more keywords
Lncrna NEAT1 Regulates Th1/Th2 in Pediatric Asthma by Targeting MicroRNA-217/GATA3
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Public Health"
DOI: 10.18502/ijph.v52i1.11671
Abstract: Background: The imbalance of immune response between helper Th1 and Th2 cells is the direct cause of asthma. It was closely related to abnormal expression of lncRNAs. However, whether lncRNAs can regulate Th1/Th2 balance in… read more here.
Keywords: mir 217; 217 gata3; lncrna neat1; gata3 ... See more keywords