Analysis of diet-induced differential methylation, expression, and interactions of lncRNA and protein-coding genes in mouse liver
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29993-4
Abstract: Long non-coding RNAs (lncRNAs) regulate expression of protein-coding genes in cis through chromatin modifications including DNA methylation. Here we interrogated whether lncRNA genes may regulate transcription and methylation of their flanking or overlapping protein-coding genes… read more here.
Keywords: methylation; expression; lncrna protein; protein coding ... See more keywords
LPI-ETSLP: lncRNA-protein interaction prediction using eigenvalue transformation-based semi-supervised link prediction.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00290d
Abstract: RNA-protein interactions are essential for understanding many important cellular processes. In particular, lncRNA-protein interactions play important roles in post-transcriptional gene regulation, such as splicing, translation, signaling and even the progression of complex diseases. However, the… read more here.
Keywords: protein; semi supervised; lpi etslp; lncrna protein ... See more keywords
A comprehensive review of methods to study lncRNA-protein interactions in solution.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Society transactions"
DOI: 10.1042/bst20220604
Abstract: The long non-coding RNAs (lncRNAs) other than rRNA and tRNA were earlier assumed to be 'junk genomic material'. However, recent advancements in genomics methods have highlighted their roles not only in housekeeping but also in… read more here.
Keywords: lncrna protein; methods study; comprehensive review; protein interactions ... See more keywords
HLPI-Ensemble: Prediction of human lncRNA-protein interactions based on ensemble strategy
Sign Up to like & getrecommendations! Published in 2018 at "RNA Biology"
DOI: 10.1080/15476286.2018.1457935
Abstract: ABSTRACT LncRNA plays an important role in many biological and disease progression by binding to related proteins. However, the experimental methods for studying lncRNA-protein interactions are time-consuming and expensive. Although there are a few models… read more here.
Keywords: hlpi; lncrna protein; hlpi ensemble; protein interactions ... See more keywords
LPI-NRLMF: lncRNA-protein interaction prediction by neighborhood regularized logistic matrix factorization
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21934
Abstract: LncRNA-protein interactions play important roles in many important cellular processes including signaling, transcriptional regulation, and even the generation and progression of complex diseases. However, experimental methods for determining proteins bound by a specific lncRNA remain… read more here.
Keywords: protein; lncrna protein; lpi nrlmf; matrix factorization ... See more keywords
LPIH2V: LncRNA-protein interactions prediction using HIN2Vec based on heterogeneous networks model
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1122909
Abstract: LncRNA-protein interaction plays an important role in the development and treatment of many human diseases. As the experimental approaches to determine lncRNA–protein interactions are expensive and time-consuming, considering that there are few calculation methods, therefore,… read more here.
Keywords: lncrna protein; network; using hin2vec; heterogeneous networks ... See more keywords
Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1136672
Abstract: Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs. In recent years, increasingly computational approaches have substituted the… read more here.
Keywords: lncrna protein; bipartite graph; biho gnn; protein interactions ... See more keywords