LncRNA PVT1 is increased in renal cell carcinoma and affects viability and migration in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24442
Abstract: Renal cell carcinoma is difficult to diagnose and unpredictable in disease course and severity. There are no specific biomarkers for diagnosis and prognosis estimation feasible in clinical practice. Long non‐coding RNAs (lncRNAs) have emerged as… read more here.
Keywords: pvt1 increased; cell carcinoma; renal cell; lncrna pvt1 ... See more keywords
LncRNA-PVT1 activates lung fibroblasts via miR-497-5p and is facilitated by FOXM1.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112030
Abstract: It is little known about the lncRNA-PVT1 effect on occupational pulmonary fibrosis, although researches show it plays an essential role in cancer. Studies reveal that lung fibroblast activation is one of the key events in… read more here.
Keywords: lncrna pvt1; lung fibroblasts; pvt1; mir 497 ... See more keywords
lncRNA PVT1 aggravates doxorubicin-induced cardiomyocyte apoptosis by targeting the miR-187-3p/AGO1 axis.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2019.101490
Abstract: OBJECTIVES To investigate the effect of long non-coding (lnc) RNA PVT1 on apoptosis induced by doxorubicin-induced cardiotoxicity. METHODS We analyzed the expression levels of lncRNA PVT1, miR-187-3p, using reverse transcription real-time quantitative PCR (RT-qPCR) in… read more here.
Keywords: mir 187; lncrna pvt1; doxorubicin induced; apoptosis ... See more keywords
Knockdown of long non-coding RNA plasmacytoma variant translocation 1 relieves ox-LDL-induced endothelial cell injury through regulating microRNA-30c-5p in atherosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2019878
Abstract: ABSTRACT Atherosclerosis (AS) is a chronic inflammatory disease involving endothelial dysfunction, and is one of the main causes of death from cardiovascular disease (CVD). Long non-coding RNA plasmacytoma variant translocation 1 (lncRNA PVT1) is overexpressed… read more here.
Keywords: cell; long non; lncrna pvt1; pvt1 ... See more keywords
The effects of LncRNA PVT1 on clinical characteristics and survival in breast cancer patients
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000024774
Abstract: Abstract Background: Currently, an increasing number of long noncoding RNAs (LncRNAs) have been reported to be abnormally expressed in human carcinomas and play a vital role in tumourigenesis. Some studies were carried out to investigate… read more here.
Keywords: cancer; cancer patients; breast cancer; effects lncrna ... See more keywords
LncRNA PVT1 Mediates Antiapoptosis and 5-Fluorouracil Resistance via Increasing Bcl2 Expression in Gastric Cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Oncology"
DOI: 10.1155/2019/9325407
Abstract: Purpose Plasmacytoma variant translocation 1 (PVT1) is a long noncoding RNA encoded by the human PVT1 gene, which has been verified to mediate tumorigenesis in gastric cancer. However, the underlying molecular mechanisms of PVT1 in… read more here.
Keywords: lncrna pvt1; gastric cancer; expression; resistance ... See more keywords
Role and Mechanism of lncRNA-pvt1 in the Pathogenesis of Acute Lymphoblastic Leukemia in Children
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/8955322
Abstract: Objective To investigate the role and mechanism of lncRNA-pvt1 in the pathogenesis of childhood acute lymphoblastic leukemia (ALL). Methods The expression of lncRNA-pvt1 in bone marrow tissues of ALL patients after initial diagnosis and complete… read more here.
Keywords: mechanism lncrna; pvt1 pathogenesis; role mechanism; acute lymphoblastic ... See more keywords
Silencing of LncRNA-PVT1 ameliorates lipopolysaccharide-induced inflammation in THP-1-derived macrophages via inhibition of the p38 MAPK signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of palliative medicine"
DOI: 10.21037/apm-21-1078
Abstract: BACKGROUND Sepsis is common in intensive care units and has a high mortality rate; yet, its pathogenesis and treatment remain unclear. Recent studies have shown that long non-coding RNA plasmacytoma variant translocation 1 (lncRNA-PVT1) plays… read more here.
Keywords: p38 mapk; pvt1; lncrna pvt1; signaling pathway ... See more keywords
LncRNA PVT1 promotes proliferation, invasion and epithelial–mesenchymal transition of renal cell carcinoma cells through downregulation of miR-16-5p
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s190239
Abstract: Background LncRNAs have recently emerged as vital regulators in the pathogenesis and development of various cancers. LncRNA PVT1 is reported to function as an oncogene in some tumors. However, the role of PVT1 in RCC… read more here.
Keywords: renal cell; cell carcinoma; invasion; cell ... See more keywords
LncRNA PVT1 regulates gallbladder cancer progression through miR-30d-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of biological regulators and homeostatic agents"
DOI: 10.23812/20-180-a-32
Abstract: Gallbladder cancer (GBC) is a malignant tumors that develops insidiously and rapidly. In this work, we explored the function of long non-coding RNA plasmacytoma variant translocation 1 (lncRNA PVT1) in modulating GBC development. PVT1 and… read more here.
Keywords: mir 30d; gbc; pvt1; gallbladder cancer ... See more keywords
Long non‑coding RNA plasmacytoma variant translocation 1 gene promotes the development of cervical cancer via the NF‑κB pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular medicine reports"
DOI: 10.3892/mmr.2019.10479
Abstract: The long noncoding RNA plasmacytoma variant translocation 1 gene (LncRNA PVT1) has an important role in tumor occurrence and development, yet the role and underlying molecular mechanisms of this RNA in cervical cancer have not… read more here.
Keywords: lncrna pvt1; cervical cancer; cancer; gene ... See more keywords