Crosstalk between the lncRNA UCA1 and microRNAs in cancer
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Letters"
DOI: 10.1002/1873-3468.13470
Abstract: Long non‐coding RNAs (lncRNAs) are a major subset of highly conserved non‐coding RNAs (ncRNAs) that consist of at least 200 nucleotides and have limited protein‐coding potential. Cumulative data have shown that lncRNAs are deregulated in… read more here.
Keywords: lncrna uca1; micrornas cancer; cancer; crosstalk lncrna ... See more keywords
The lncRNA 'UCA1' modulates the response to chemotherapy of ovarian cancer through direct binding to miR-27a-5p and control of UBE2N levels.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.13045
Abstract: Ovarian cancer (OC) is the leading cause of death in patients with gynecologic cancers. Due to late diagnosis and resistance to chemotherapy, the 5-year survival rate in patients with OC is below 40%. We observed… read more here.
Keywords: chemotherapy; mir 27a; response; lncrna uca1 ... See more keywords
LncRNA UCA1 is necessary for TGF‐β‐induced epithelial–mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12533
Abstract: The 5‐year survival rate of patients with glioma is < 5%, and therefore there is an urgent need to find novel potential targets for facilitating its diagnosis and treatment. The long non‐coding RNA (lncRNA) UCA1… read more here.
Keywords: stemness; glioma; lncrna uca1; slug ... See more keywords
Involvement of blood lncRNA UCA1 in sepsis development and prognosis, and its correlation with multiple inflammatory cytokines
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24392
Abstract: Sepsis is a highly life‐threatening disease. Long non‐coding RNA urothelial carcinoma associated 1 (lncRNA UCA1) participates in the processes of inflammation and organ injury in several diseases, whereas its role in sepsis patients is still… read more here.
Keywords: sepsis; blood lncrna; sepsis development; involvement blood ... See more keywords
LncRNA UCA1 Suppresses the Inflammation Via Modulating miR-203-Mediated Regulation of MEF2C/NF-κB Signaling Pathway in Epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02952-9
Abstract: Although many advances have been made in the pathogenesis of epilepsy recently, the pathological mechanisms of epilepsy are still largely unknown. Exploring the pathological mechanisms and developing novel therapeutic strategies for epilepsy are urgently needed.… read more here.
Keywords: mir 203; mef2c; expression; lncrna uca1 ... See more keywords
LncRNA-UCA1 regulates lung adenocarcinoma progression through competitive binding to miR-383
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2111929
Abstract: ABSTRACT The present study aimed to assess the role of the long non-coding RNA-urothelial cancer associated 1 (lncRNA-UCA1)/microRNA (miR)-383/vascular endothelial growth factor A (VEGFA) axis in regulating lung adenocarcinoma physiology through in vivo and in… read more here.
Keywords: cell; lung adenocarcinoma; expression; mir 383 ... See more keywords
Expression of Concern: Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2137766
Abstract: Downregulated lncRNA UCA1 acts as ceRNA to adsorb microRNA-498 to repress proliferation, invasion and epithelial mesenchymal transition of esophageal cancer cells by decreasing ZEB2 expression. read more here.
Keywords: uca1 acts; cerna adsorb; acts cerna; expression ... See more keywords
Silence of lncRNA UCA1 Represses the Growth and Tube Formation of Human Microvascular Endothelial Cells Through miR-195
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000493454
Abstract: Background/Aims: Recent studies have suggested that several lncRNAs contribute to the angiogenic function of endothelial cells. Herein, we set out to reveal whether lncRNA UCA1 has functions in endothelial angiogenesis. Methods: The expression levels of… read more here.
Keywords: mir 195; lncrna uca1; tube formation; silence lncrna ... See more keywords
LncRNA UCA1 Accelerates the Progression of Ulcerative Colitis via Mediating the miR-331-3p/BRD4 Axis
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DOI: 10.2147/ijgm.s304837
Abstract: Background Ulcerative colitis (UC) has become one of the fastest-growing severe diseases worldwide with high morbidity. This research aimed to explore the function of lncRNA UCA1 in UC progression. Methods RT-qPCR analysis was used to… read more here.
Keywords: mir 331; ulcerative colitis; 331 brd4; lncrna uca1 ... See more keywords
LncRNA UCA1 regulates proliferation, migration and invasion of cervical cancer cells by targeting miR-145.
Sign Up to like & getrecommendations! Published in 2020 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202004_20816
Abstract: OBJECTIVE Finding a key target for the development of cervical cancer is conducive to the treatment of cervical cancer. LncRNA UCA1 plays a role in multiple tumors, such as the digestive tract and bladder. However,… read more here.
Keywords: mir 145; lncrna uca1; group; cervical cancer ... See more keywords