CRISPRa-mediated NEAT1 lncRNA upregulation induces formation of intact paraspeckles.
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DOI: 10.1016/j.bbrc.2018.08.158
Abstract: Long noncoding RNAs (lncRNAs) are fundamental genomic regulatory factors under various physiological and pathological conditions. A class of lncRNAs termed architectural RNAs (arcRNAs) plays an essential scaffolding role in building nuclear bodies. NEAT1 arcRNA is… read more here.
Keywords: crispra mediated; sam system; neat1 lncrna; lncrna upregulation ... See more keywords