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   Articles with "lncrna xist" as a keyword



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Downregulating LncRNA XIST attenuated contrast-induced nephropathy injury via regulating miR-133a-3p/NLRP3 axis

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recommendations! Published in 2021 at "Journal of Thrombosis and Thrombolysis"

DOI: 10.1007/s11239-020-02369-0

Abstract: Long non-coding RNA X-inactive specific transcript (LncRNA XIST) is involved in several diseases. However, the molecular mechanism of XIST and its relation with miR-133a-3p in contrast-induced nephropathy (CIN) remained vague. Sprague–Dawley (SD) rats were assigned… read more here.

Keywords: xist; contrast induced; mir 133a; induced nephropathy ... See more keywords
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The role of lncRNA XIST/miR-211 axis in modulating the proliferation and apoptosis of osteoarthritis chondrocytes through CXCR4 and MAPK signaling.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.07.015

Abstract: Long noncoding RNAs (lncRNAs) participate in multiple diverse diseases, including osteoarthritis (OA). Here, we explored the role of lncRNA XIST in OA and identified the potential molecular mechanisms. The expression of XIST in cartilage samples… read more here.

Keywords: xist; apoptosis; mir 211; proliferation ... See more keywords
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Long non-coding RNA XIST promotes TGF-β-induced epithelial-mesenchymal transition by regulating miR-367/141-ZEB2 axis in non-small-cell lung cancer.

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recommendations! Published in 2018 at "Cancer letters"

DOI: 10.1016/j.canlet.2018.01.036

Abstract: Growing evidence shows that lncRNA XIST functions as an oncogene accelerating tumor progression. Transforming growth factor β (TGF-β)-induced epithelial-mesenchymal transition (EMT) plays a key role in tumor metastasis. However, it is still unclear whether lncRNA… read more here.

Keywords: zeb2; xist; mir 367; tgf induced ... See more keywords
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lncRNA XIST attenuates hypoxia-induced H9c2 cardiomyocyte injury by targeting the miR-122-5p/FOXP2 axis.

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recommendations! Published in 2019 at "Molecular and cellular probes"

DOI: 10.1016/j.mcp.2019.101500

Abstract: OBJECTIVE To investigate the effect of lncRNA XIST on apoptosis induced by hypoxia. METHODS We analyzed the expression levels of lncRNA XIST and miR-122-5p using RT-qPCR in hypoxia-induced cardiomyocytes. The mechanism by which lncRNA XIST… read more here.

Keywords: expression; h9c2; mir 122; cell ... See more keywords
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LncRNA XIST promotes the progression of laryngeal squamous cell carcinoma via sponging miR-125b-5p to modulate TRIB2

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recommendations! Published in 2020 at "Bioscience Reports"

DOI: 10.1042/bsr20193172

Abstract: OBJECTIVE X inactivate-specific transcript (XIST) is an attractive long noncoding RNA (lncRNA) functioning as an indicator of various human tumors, including laryngeal squamous cell carcinoma (LSCC). This study was conducted to explore a novel regulatory… read more here.

Keywords: lncrna xist; mir 125b; cell; lscc ... See more keywords
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LncRNA NKILA Inhibits Retinoblastoma by Downregulating lncRNA XIST

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recommendations! Published in 2019 at "Current Eye Research"

DOI: 10.1080/02713683.2019.1606253

Abstract: ABSTRACT Purpose: Although retinoblastoma is rare but can be deadly in some severe cases. To find novel therapeutic targets for retinoblastoma, we explored the potential role of lncRNA NKILA in retinoblastoma. Results: We found that,… read more here.

Keywords: lncrna nkila; overexpression; inhibits retinoblastoma; nkila inhibits ... See more keywords
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Role of lncRNA XIST/microRNA-19/PTEN network in autophagy of nucleus pulposus cells in intervertebral disc degeneration via the PI3K/Akt signaling pathway

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recommendations! Published in 2021 at "Cell Cycle"

DOI: 10.1080/15384101.2021.1924450

Abstract: ABSTRACT Intervertebral disc degeneration (IVDD) is a complicated pathological condition accompanying with low back pain. This study was designed to figure out the mechanism of lncRNA XIST in IVDD. Abnormally expressed lncRNAs in IVDD patients… read more here.

Keywords: xist; disc degeneration; pi3k akt; signaling pathway ... See more keywords
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Long non-coding RNA-X-inactive specific transcript inhibits cell viability, and induces apoptosis through the microRNA-30c-5p/Bcl2-like protein 11 signaling axis in human granulosa-like tumor cells

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2080366

Abstract: ABSTRACT The role of long noncoding RNAs (lncRNAs) is being actively explored in polycystic ovary syndrome (PCOS). Recent research has shown that long non-coding RNA (lncRNA) X–inactive Specific Transcript (XIST) is overexpressed in patients with… read more here.

Keywords: non coding; lncrna xist; physiology; granulosa ... See more keywords
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Prognostic role of long non-coding RNA XIST expression in patients with solid tumors: a meta-analysis

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recommendations! Published in 2018 at "Cancer Cell International"

DOI: 10.1186/s12935-018-0535-x

Abstract: BackgroundThe aberrant expression of long non-coding RNA (lncRNA) X inactivate-specific transcript (XIST) has been demonstrated to be involved in the tumourigenesis and the development of various cancers. Therefore, we conducted a meta-analysis to assess the… read more here.

Keywords: solid tumors; expression; lncrna xist; xist expression ... See more keywords
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lncRNA Xist Regulates Osteoblast Differentiation by Sponging miR-19a-3p in Aging-induced Osteoporosis.

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recommendations! Published in 2020 at "Aging and Disease"

DOI: 10.14336/ad.2019.0724

Abstract: The switch between osteogenic and adipogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) plays a key role in aging-induced osteoporosis. In this study, miR-19a-3p was obviously downregulated in BMSCs from aged humans and mice.… read more here.

Keywords: bmscs; differentiation; lncrna xist; mir 19a ... See more keywords
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LncRNA XIST acts as a ceRNA sponging miR-185-5p to modulate pancreatic cancer cell proliferation via targeting CCND2

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recommendations! Published in 2020 at "Translational cancer research"

DOI: 10.21037/tcr.2020.01.26

Abstract: Department of Oncology, Second Xiangya Hospital, Central South University, Changsha 410011, China Contributions: (I) Conception and design: YP Wang; (II) Administrative support: YP Wang, Y Huang; (III) Provision of study materials or patients: T Hou;… read more here.

Keywords: cerna sponging; acts cerna; xist acts; cancer ... See more keywords