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Published in 2019 at "Investigational New Drugs"
DOI: 10.1007/s10637-019-00884-3
Abstract: Temozolomide is a first line anti-tumor drug used for the treatment of patients with Glioblastoma multiforme (GBM). However, the drug resistance to temozolomide limits its clinical application. Therefore, novel strategies to overcome chemoresistance are desperately…
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Keywords:
mrnas lncrnas;
glioblastoma;
lncrnas circrnas;
expression ... See more keywords
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1
Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-2757-0
Abstract: Cross-talk between competitive endogenous RNAs (ceRNAs) may play a critical role in revealing potential mechanisms of tumor development and physiology. Glioblastoma is the most common type of malignant primary brain tumor, and the mechanisms of…
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Keywords:
rna;
analyzing interactions;
lncrnas circrnas;
mirnas lncrnas ... See more keywords
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Published in 2020 at "Neurotherapeutics"
DOI: 10.1007/s13311-020-00881-y
Abstract: Neuropathic pain (NP) is directly caused by an injury or disease of the somatosensory nervous system. It is a serious type of chronic pain that is a burden to the economy and public health. Although…
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Keywords:
mirnas mrnas;
among lncrnas;
lncrnas circrnas;
circrnas mirnas ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-00176-y
Abstract: SART and PMM are mainly composed of oxidative myofibers and glycolytic myofibers, respectively, and myofiber types profoundly influence postnatal muscle growth and meat quality. SART and PMM are composed of lncRNAs and circRNAs that participate…
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Keywords:
novel circ;
oxidative myofibers;
myofiber;
sart ... See more keywords
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Published in 2022 at "Bioscience Reports"
DOI: 10.1042/bsr20220645
Abstract: Abstract In recent years, breast cancer attracts more and more attention because of its high incidence. To explore the molecular functions and mechanisms, we performed RNA sequencing on the tumor tissues and their paired normal…
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Keywords:
lncrnas circrnas;
breast cancer;
differential expression;
cancer ... See more keywords
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1
Published in 2019 at "Acta Physiologica"
DOI: 10.1111/apha.13356
Abstract: The multistep biological process of myogenesis is regulated by a variety of myoblast regulators, such as myogenic differentiation antigen, myogenin, myogenic regulatory factor, myocyte enhancer factor2A‐D and myosin heavy chain. Proliferation and differentiation during skeletal…
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Keywords:
skeletal muscle;
muscle;
lncrnas circrnas;
roles lncrnas ... See more keywords
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1
Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/6278526
Abstract: Phosgene exposure can cause acute lung injury (ALI), for which there is no currently available effective treatment. Mesenchymal stem cells (MSCs) which have been proven to have therapeutic potential and be helpful in the treatment…
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Keywords:
mrnas lncrnas;
lncrnas circrnas;
phosgene induced;
acute lung ... See more keywords
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1
Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0261293
Abstract: Intramuscular fat content is an important determinant of meat quality, and preadipocyte differentiation plays a critical role in intramuscular fat deposition in pigs. However, many types of RNA differentiation, including messenger RNA (mRNA), long non-coding…
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Keywords:
adipogenesis;
lncrnas circrnas;
congjiang pigs;
guizhou congjiang ... See more keywords
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Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.625846
Abstract: Severe acute pancreatitis (SAP) is an acute digestive system disease with high morbidity mortality and hospitalization rate worldwide, due to various causes and unknown pathogenesis. In recent years, a large number of studies have confirmed…
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Keywords:
acute pancreatitis;
severe acute;
lncrnas circrnas;
circrna ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.810317
Abstract: Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that affect synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra-articular disorders. However, the pathogenesis of RA is still…
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Keywords:
lncrnas circrnas;
interactions lncrnas;
diagnosis treatment;
rheumatoid arthritis ... See more keywords
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Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.01720
Abstract: Cervical cancer is the third most common cancer worldwide and the fourth leading cause of cancer-associated mortality in women. Accumulating evidence indicates that long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) may play key roles…
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Keywords:
coding rnas;
cervical cancer;
lncrnas circrnas;
long non ... See more keywords