Individual risk of post-ivermectin serious adverse events in subjects infected with Loa loa
Sign Up to like & getrecommendations! Published in 2020 at "EClinicalMedicine"
DOI: 10.1016/j.eclinm.2020.100582
Abstract: Background Implementation of onchocerciasis elimination programmes has been delayed in Central Africa because of the risk of ivermectin-related serious adverse events (SAEs) in individuals with high Loa loa microfilarial densities (MFD). We developed the first… read more here.
Keywords: risk; loa loa; sae; serious adverse ... See more keywords
Encephalopathy in a patient with loiasis treated with albendazole: A case report.
Sign Up to like & getrecommendations! Published in 2019 at "Parasitology international"
DOI: 10.1016/j.parint.2019.102006
Abstract: BACKGROUND Loiasis is a vector-borne parasitic infection endemic across many areas of Central and West Africa. Its treatment is tricky due to the risk of serious neurologic adverse events occurring after the administration of microfilaricidal… read more here.
Keywords: loiasis; loa loa; treatment; case ... See more keywords
Mouse models of Loa loa
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DOI: 10.1038/s41467-019-09442-0
Abstract: Elimination of the helminth disease, river blindness, remains challenging due to ivermectin treatment-associated adverse reactions in loiasis co-infected patients. Here, we address a deficit in preclinical research tools for filarial translational research by developing Loa… read more here.
Keywords: loa loa; loa mouse; loa; ivermectin treatment ... See more keywords
Interdevice agreement in the measurement of physiognomy parameters and frame angles to prescribe progressive addition lenses
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DOI: 10.1080/08164622.2021.2006042
Abstract: ABSTRACT Clinical relevance Ophthalmic lens adaptation requires accurate measurements of physiognomy parameters and frame angles, with a great impact on subject vision, especially when personalised progressive addition lenses are prescribed. Background The aim of this… read more here.
Keywords: agreement; loa; progressive addition; frame angles ... See more keywords
Loa loa filariasis in a tropical savanna area: report of one case in Ouagadougou
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DOI: 10.1111/ijd.14782
Abstract: Loa loa filariasis is usually found in the forest areas of Central and West Africa. We report a case that was diagnosed in Ouagadougou (Burkina Faso), a savanna area. The patient lived in Gabon but… read more here.
Keywords: savanna area; loa loa; case; report ... See more keywords
Geostatistical modelling enables efficient safety assessment for mass drug administration with ivermectin in Loa loa endemic areas through a combined antibody and LoaScope testing strategy for elimination of onchocerciasis
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010189
Abstract: The elimination of onchocerciasis through community-based Mass Drug Administration (MDA) of ivermectin (Mectizan) is hampered by co-endemicity of Loa loa, as individuals who are highly co-infected with Loa loa parasites can suffer serious and occasionally… read more here.
Keywords: loascope; mass drug; elimination onchocerciasis; strategy ... See more keywords
Comparison of six methods for Loa loa genomic DNA extraction
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DOI: 10.1371/journal.pone.0265582
Abstract: Objectives Good-quality and sufficient DNA is essential for diagnostics and vaccine development. We aimed to compare six DNA extraction techniques applied to Loa loa microfilariae in order to evaluate the purity and integrity of extracts… read more here.
Keywords: dna extraction; dna; loa loa; phenol chloroform ... See more keywords
Colorimetric and Real-Time Loop-Mediated Isothermal Amplification (LAMP) for Detection of Loa loa DNA in Human Blood Samples
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12051079
Abstract: Loiasis, caused by the filarial nematode Loa loa, is endemic in Central and West Africa. Loa loa has been associated with severe adverse reactions in high Loa-infected individuals receiving ivermectin during mass drug administration programs… read more here.
Keywords: loa; lamp; microscopy; real time ... See more keywords