Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded hydrogels.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.01.021
Abstract: Mesenchymal stromal/stem cells (MSCs) have demonstrated pro-healing properties including an anti-inflammatory cytokine profile and the promotion of angiogenesis via expression of growth factors in pre-clinical models. MSCs encapsulated in poly(ethylene glycol) diacrylate (PEGdA) and thiolated… read more here.
Keywords: minocycline; stromal stem; wound healing; mesenchymal stromal ... See more keywords
Nanoparticle-loaded hydrogels as a pathway for enzyme-triggered drug release in ophthalmic applications.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.11.053
Abstract: The aim of this study was to develop nanoparticle loaded hydrogel based contact lenses that could be used for ocular drug delivery. Two potential contact lens platforms for controlled ophthalmic drug delivery were developed by… read more here.
Keywords: enzyme triggered; drug delivery; nanoparticle loaded; drug ... See more keywords
Therapeutic effect of imatinib-loaded hydrogels on leukemia by inhibiting excessive apoptosis of white blood cells
Sign Up to like & getrecommendations! Published in 2023 at "Materials Express"
DOI: 10.1166/mex.2023.2363
Abstract: Chronic myelocytic leukemia (CML) refers to a malignant proliferative disease of the bone marrow characterized by abnormalities of multipotent stem cells on the Philadelphia chromosome and accounts for approximately 20% of all leukemias. Imatinib is… read more here.
Keywords: effect imatinib; imatinib; imatinib loaded; hydrogels leukemia ... See more keywords
Characteristics of culture-condition stimulated exosomes or their loaded hydrogels in comparison with other extracellular vesicles or MSC lysates
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1016833
Abstract: Recently, it has become popular to study the use of extracellular vesicles (EVs) secreted by stem cells to repair damaged tissues or lost cells. Various cell types and physiological fluids release EVs, and they play… read more here.
Keywords: culture condition; extracellular vesicles; condition stimulated; exosomes loaded ... See more keywords
Exosome Mimetics-Loaded Hydrogel Accelerates Wound Repair by Transferring Functional Mitochondrial Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.866505
Abstract: Loading human umbilical mesenchymal stem cell (hUMSC) derived exosomes onto hydrogel scaffolds is a strategy for rapid wound healing. The clinical application of exosomes is hindered by low production, and exosome mimetics could be substituted… read more here.
Keywords: exosome mimetics; exosome mimetic; hydrogel; mimetics loaded ... See more keywords
Polymeric Nanoparticles-Loaded Hydrogels for Biomedical Applications: A Systematic Review on In Vivo Findings
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14051010
Abstract: Clinically available medications face several hurdles that limit their therapeutic activity, including restricted access to the target tissues due to biological barriers, low bioavailability, and poor pharmacokinetic properties. Drug delivery systems (DDS), such as nanoparticles… read more here.
Keywords: drug; systematic review; loaded hydrogels; biomedical applications ... See more keywords
Analgesic and potentiated photothermal therapy with ropivacaine-loaded hydrogels
Sign Up to like & getrecommendations! Published in 2023 at "Theranostics"
DOI: 10.7150/thno.81325
Abstract: Rationale: Tumor ablation can cause severe pain to patients, but there is no satisfactory means of analgesia available. In addition, recurrence of residual tumors due to incomplete ablation threatens patient safety. Photothermal therapy (PTT), a… read more here.
Keywords: photothermal therapy; ptt; pain; tumor ... See more keywords