A Multifunctional Nanocomposite Hydrogel Delivery System Based on Dual‐Loaded Liposomes for Scarless Wound Healing
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202401619
Abstract: Increased inflammatory responses and oxidative stress at the wound site following skin trauma impair healing. Furthermore, skin scarring places fibroblasts under severe mechanical stress and aggravates pathological fibrosis. A novel liposomal composite hydrogel is engineered… read more here.
Keywords: system; nanocomposite hydrogel; hydrogel; scarless wound ... See more keywords
Neutrophils Enable Local and Non-Invasive Liposome Delivery to Inflamed Skeletal Muscle and Ischemic Heart.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202003598
Abstract: Uncontrolled inflammation is a major pathological factor underlying a range of diseases including autoimmune conditions, cardiovascular disease, and cancer. Improving localized delivery of immunosuppressive drugs to inflamed tissue in a non-invasive manner offers significant promise… read more here.
Keywords: skeletal muscle; loaded liposomes; inflamed skeletal; delivery ... See more keywords
Metabolic Reprogramming of Macrophages by Biomimetic Melatonin‐Loaded Liposomes Effectively Attenuates Acute Gouty Arthritis in a Mouse Model
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202410107
Abstract: Gouty arthritis is characterized by an acute inflammatory response triggered by monosodium urate (MSU) crystals deposited in the joints and periarticular tissues. Current treatments bring little effects owing to serious side effects, necessitating the exploration… read more here.
Keywords: gouty arthritis; loaded liposomes; melatonin loaded; arthritis ... See more keywords
Nanoscale Liposomes Co‐Loaded with Irinotecan Hydrochloride and Thalidomide for Colorectal Cancer Synergistic Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Bioscience"
DOI: 10.1002/mabi.202400478
Abstract: Irinotecan hydrochloride (CPT‐11) is one of the first‐line drugs used in the clinical treatment of colorectal cancer (CRC). However, the concomitant adverse effect of delayed diarrhea has hindered its clinical use. CPT‐11 combined with Thalidomide… read more here.
Keywords: colorectal cancer; loaded liposomes; irinotecan hydrochloride; therapy ... See more keywords
Properties and bioavailability assessment of shrimp astaxanthin loaded liposomes
Sign Up to like & getrecommendations! Published in 2018 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-018-0495-x
Abstract: This study aimed to investigate the effects of phospholipid composition on the properties and bioavailability of astaxanthin-loaded liposomes using cell culture. Two mixtures of phospholipids with different proportions of phosphatidylcholine (PC, 23% and 70%) were… read more here.
Keywords: loaded liposomes; assessment shrimp; bioavailability assessment; properties bioavailability ... See more keywords
Effect of Spray Drying on Physicochemical Stability and Antioxidant Capacity of Rosa pimpinellifolia Fruit Extract-Loaded Liposomes Conjugated with Chitosan or Whey Protein During In Vitro Digestion
Sign Up to like & getrecommendations! Published in 2024 at "Food and Bioprocess Technology"
DOI: 10.1007/s11947-024-03317-z
Abstract: Spray drying is a well-established, energy efficient, and scalable process widely used in the food industry, however it may lead to thermal degradation of susceptible compounds, such as (poly)phenols, resulting in biological activity loss to… read more here.
Keywords: spray; poly phenols; physicochemical stability; extract ... See more keywords
Liposils: An effective strategy for stabilizing Paclitaxel loaded liposomes by surface coating with silica
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.06.025
Abstract: &NA; The present work aims at improving stability of paclitaxel (PTX) loaded liposomes by its coating with silica on the surface by a modified sol‐gel method. Effect of various components of liposomes such as phosphatidylcholine… read more here.
Keywords: loaded liposomes; ptx; stability; coating silica ... See more keywords
Effect of β-sitosterol on the curcumin-loaded liposomes: Vesicle characteristics, physicochemical stability, in vitro release and bioavailability.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.04.077
Abstract: In this work, the effect of β-sitosterol (Sito) on vesicle characteristics, physicochemical stability as well as the in vitro release and bioavailability of curcumin-loaded liposomes (Cur-LP) was studied. When 20-33 mol% of Sito was incorporated, encapsulation… read more here.
Keywords: bioavailability; curcumin; loaded liposomes; stability ... See more keywords
Manufacturing drug co-loaded liposomal formulations targeting breast cancer: influence of preparative method on liposomes characteristics and in vitro toxicity.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119926
Abstract: Developing more efficient manufacturing methods for nano therapeutic systems is becoming important, not only to better control their physico-chemical characteristics and therapeutic efficacy but also to ensure scale-up is cost-effective. The principle of cross-flow chemistry… read more here.
Keywords: loaded liposomes; method; breast cancer; umbelliprenin loaded ... See more keywords
A supercritical assisted process for the production of amoxicillin-loaded liposomes for antimicrobial applications
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Supercritical Fluids"
DOI: 10.1016/j.supflu.2020.104842
Abstract: Abstract Most common limitations of drug carriers, such as liposomes, are low Encapsulation Efficiency (EE) and possible degradation of the encapsulated drugs. Several techniques were developed to overcome these problems; among these, Supercritical assisted Liposome… read more here.
Keywords: loaded liposomes; lipid ratio; supercritical assisted; assisted process ... See more keywords
Optimized spray-drying of zinc sulfate-loaded liposomes: physicochemical characterization and in vitro release assessment
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-05948-4
Abstract: Zinc, a vital trace element plays a crucial role in various physiological functions, faces challenges in bioavailability due to dietary and pharmaceutical interactions. To enhance its delivery and stability, this study formulated spray-dried zinc sulfate-loaded… read more here.
Keywords: spray; release; zinc; loaded liposomes ... See more keywords