Antitumor efficacy and cardiotoxic effect of doxorubicin-loaded mixed micelles in 4T1 murine breast cancer model. Comparative studies using Doxil® and free doxorubicin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101506
Abstract: Abstract Doxorubicin-loaded mixed micelles (DOX-micelles) were formulated employing TPGS and a poloxamine (Tetronic® T1107) in order to investigate their pharmaceutical application as an alternative anticancer nanotherapy. DOX-micelles presented unimodal behaviour, exhibiting average size values of… read more here.
Keywords: dox micelles; doxorubicin; loaded mixed; effect ... See more keywords
Improved oral absorption and anti-lung cancer activity of paclitaxel-loaded mixed micelles
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DOI: 10.1080/10717544.2016.1245370
Abstract: Abstract The aim of this study was to establish a paclitaxel (PTX)-loaded mixed micelle delivery system (PTX-TP-M) with vitamin E-TPGS (TPGS) and Plasdone®S-630 Copovidone (PVPS630) as carriers to improve the solubility, oral absorption, and anti-tumor… read more here.
Keywords: absorption; loaded mixed; ptx; mixed micelles ... See more keywords
Dapsone-Loaded Mixed Micellar Gel for Treatment OF Acne Vulgaris
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DOI: 10.1208/s12249-023-02564-1
Abstract: Mixed polymeric micelles are potential nanocarriers for topical drug delivery. Dapsone (DAP) is an antibacterial used as anti-acne agent, but challenged by low water solubility and poor skin permeability. In the present study, DAP-loaded mixed… read more here.
Keywords: dap; mixed micellar; dapsone; loaded mixed ... See more keywords