Ultrastructural and physicochemical characterization of pH receptive chlorhexidine-loaded poly-L-glycolic acid-modified orthodontic adhesive.
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy research and technique"
DOI: 10.1002/jemt.23968
Abstract: This study aims to evaluate the feasibility of chlorhexidine (CHX)-loaded poly-L-glycolic acid (PLGA) nanoparticles as a modifier of a commercial orthodontic adhesive via the assessment of physicochemical, biological, and mechanical properties at tooth-bracket interface. CHX-loaded… read more here.
Keywords: plga nanoparticles; loaded plga; chx loaded; orthodontic adhesive ... See more keywords
RETRACTED: In Vitro Neuroprotective Effect Evaluation of Donepezil‐Loaded PLGA Nanoparticles‐Embedded PVA/PEG Nanofibers on SH‐SY5Y Cells and AP‐APP Plasmid Related Alzheimer Cell Line Model
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Materials and Engineering"
DOI: 10.1002/mame.202400160
Abstract: Recently developed nanoparticles and nanofibers present new brain‐specific treatment strategies, especially for Alzheimer's disease treatment. In this study, donepezil (DO)‐loaded PLGA nanoparticles (DNP) are embedded in PVA/PEG nanofibers (DNPF) produced by pressurized gyration for sublingual… read more here.
Keywords: alzheimer; pva peg; donepezil loaded; loaded plga ... See more keywords
Comparative study of cilnidipine loaded PLGA nanoparticles: process optimization by DoE, physico-chemical characterization and in vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-020-00732-5
Abstract: Cilnidipine (CND) is known to have low oral bioavailability due to its poor aqueous solubility, low dissolution rate, and high gut wall metabolism. In the present study, CND-loaded PLGA nanoparticles (CND-PLGA-NPs) were prepared with two… read more here.
Keywords: cnd plga; plga nanoparticles; cnd; loaded plga ... See more keywords
Oxcarbazepine free or loaded PLGA nanoparticles as effective intranasal approach to control epileptic seizures in rodents
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.11.002
Abstract: &NA; The brain as a target for drug delivery is a challenge in pharmaceutical research. Among the several proposed strategies, the intranasal route represents a good strategy to deliver drugs to the brain. The goal… read more here.
Keywords: loaded plga; plga nps; epileptic seizures; brain ... See more keywords
Resveratrol-loaded PLGA nanoparticles functionalized with red blood cell membranes as a biomimetic delivery system for prolonged circulation time
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.101369
Abstract: Abstract Resveratrol (RES) shows excellent pharmacological activities but is limited by a very short half-life. In this study, red blood cell (RBC) membranes camouflaging RES-loaded PLGA NPs (RBC-RES-NPs) were successfully designed and synthesized. The resulting… read more here.
Keywords: red blood; resveratrol; loaded plga; blood cell ... See more keywords
Multifunctional magnetic-polymeric nanoparticles based ferrofluids for multi-modal in vitro cancer treatment using thermotherapy and chemotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2019.111549
Abstract: Abstract In this work, we have developed novel multifunctional magnetic-polymeric nanoparticles (MMPNs) based ferrofluids by encapsulating oleylamine (OM)-coated hydrophobic superparamagnetic iron oxide nanoparticles (SPIONs) inside the poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) individually, and along with… read more here.
Keywords: plga nps; based ferrofluids; plga; loaded plga ... See more keywords
Controllable Subtractive Nanoimprint Lithography for Precisely Fabricating Paclitaxel-loaded PLGA Nanocylinders to Enhance Anticancer Efficacy.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b21346
Abstract: Nanoimprint lithography presents a new strategy for preparing uniform nanostructures with predefined sizes and shapes, and has the potential for developing nanosized drug delivery systems. However, current nanoimprint lithography is a type of additive nanofabrication… read more here.
Keywords: loaded plga; paclitaxel loaded; nanoimprint; nanoimprint lithography ... See more keywords
Development of donepezil hydrochloride-loaded PLGA-based nanoparticles for Alzheimer’s disease treatment
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-95792-3
Abstract: In recent years, nanoparticle (NP) systems have demonstrated significant promise in pharmaceutical applications. This study focused on the development of donepezil hydrochloride-loaded PLGA-NPs, prepared using the ‘Double Emulsion Solvent Evaporation’ method. The impact of varying… read more here.
Keywords: alzheimer disease; stability; hydrochloride loaded; donepezil hydrochloride ... See more keywords
Novel urea derivative-loaded PLGA nanoparticles to inhibit caries-associated Streptococcus mutans
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra09314b
Abstract: Caries is the most common chronic infectious disease in the human oral cavity and the existing anti-caries agents may lead to drug resistance and microecological imbalance. A novel urea derivative, 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea, has a potentially prominent… read more here.
Keywords: loaded plga; urea derivative; novel urea; streptococcus mutans ... See more keywords
Influence of drying processes on the structures, morphology and in vitro release profiles of risperidone-loaded PLGA microspheres
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2019.1582723
Abstract: Abstract The purpose of this study was to investigate the influences of drying methods on the risperidone (RIS) release profiles of RIS-loaded PLGA microspheres. These microspheres were fabricated with an O/W emulsion solvent evaporation method.… read more here.
Keywords: plga microspheres; influence; release profiles; loaded plga ... See more keywords
Electrospinning of linezolid loaded PLGA nanofibers: effect of solvents on its spinnability, drug delivery, mechanical properties, and antibacterial activities
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2019.1706550
Abstract: Objective: The choice of a desirable solvent/solvent system is fundamental for optimization of electrospinning by altering the rheological and electrostatic properties of the polymer solutions.Meth... read more here.
Keywords: electrospinning linezolid; plga nanofibers; nanofibers effect; drug ... See more keywords