Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7538
Abstract: Curcumin, a plant‐derived compound, has various well‐known biological effects (anti‐inflammatory, antioxidant, antitumor, among others) as well as some important limitations for formulators, such as poor water solubility and low oral bioavailability. Its nanoencapsulation is reported… read more here.
Keywords: polymeric nanocapsules; curcumin; curcumin loaded; systematic review ... See more keywords
Formulation and Characterization of Curcumin Loaded Polymeric Micelles Produced via Continuous Processing.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119340
Abstract: A continuous processing platform was developed to produce polymeric micelles. A block copolymer of mPEG (5kD)-PCL (2kD) was used as the model drug carrier. The polymeric micelles were produced using an innovative co-axial turbulent jet… read more here.
Keywords: continuous processing; loaded polymeric; curcumin loaded; drug ... See more keywords
Drug-loaded polymeric films as a promising tool for the treatment of periodontitis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.04.034
Abstract: Abstract This study addresses the fabrication and characterization of poly-caprolactone/alginic acid based drug-containing polymeric films. Two basic drugs used in the treatment of periodontal diseases (metronidazole and doxycycline) were investigated. The polymeric films were characterized… read more here.
Keywords: films promising; drug; treatment; polymeric films ... See more keywords
Evaluation of Pharmacokinetics, Biodistribution, and Antimalarial Efficacy of Artemether-Loaded Polymeric Nanorods.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00507
Abstract: Artemether oily injection is recommended for the treatment of severe malaria by the intramuscular route. The major limitations of the artemisinin combination therapy are erratic absorption from the injection site and high dosing frequency due… read more here.
Keywords: polymeric nanorods; artemether loaded; microscopy; pharmacokinetics biodistribution ... See more keywords
Self-Assembled Fingolimod (FTY720)-Loaded Polymeric Micelles Protect Brain from Injury in Intracerebral Hemorrhage.
Sign Up to like & getrecommendations! Published in 2025 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.5c00231
Abstract: Polymeric micelles, originating from the self-assembly of amphiphilic block copolymers, presenting a lipophilic core and hydrophilic shell, are widely used as nanoscale drug-delivery systems. In the present study, the functional nanosized FTY720-loaded polymeric micelles (NP@FTY720)… read more here.
Keywords: loaded polymeric; fty720; polymeric micelles; self assembled ... See more keywords
Preclinical efficacy and mechanisms of statin-loaded polymeric nanocapsules: a meta-analysis of tumor lipid metabolism inhibition
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-22302-w
Abstract: Lipid metabolism plays a pivotal role in tumor growth and survival, with altered lipid pathways being associated with cancer progression. Statins, well-known for their cholesterol-lowering properties, have emerged as potential anticancer agents by targeting lipid… read more here.
Keywords: statin loaded; loaded polymeric; polymeric nanocapsules; efficacy ... See more keywords
Synergistic anticancer activity of resveratrol-loaded polymeric nanoparticles and sunitinib in colorectal cancer treatment
Sign Up to like & getrecommendations! Published in 2025 at "Royal Society Open Science"
DOI: 10.1098/rsos.241817
Abstract: The development of novel and effective treatment strategies, particularly through drug combinations, can significantly enhance therapeutic outcomes. This study explores the innovative combination of resveratrol (RES), a phenolic compound, with sunitinib (SUNI), a multitarget tyrosine… read more here.
Keywords: loaded polymeric; colorectal cancer; treatment; anticancer activity ... See more keywords
Synthesis and in vitro evaluation of natural drug loaded polymeric films for cardiovascular applications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bioactive and Compatible Polymers"
DOI: 10.1177/08839115221085735
Abstract: Drug eluting stents (DES) can efficiently reduce the atherosclerosis and restenosis issues of coronary artery as compared to bare metal stents due to the presence of pharmaceutically active agent on their surface. Nevertheless, the arising… read more here.
Keywords: natural drug; polymeric films; drug loaded; synthesis vitro ... See more keywords
Zebrafish: A Useful Animal Model for the Characterization of Drug-Loaded Polymeric NPs
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092252
Abstract: The use of zebrafish (ZF) embryos as an in vivo model is increasingly attractive thanks to different features that include easy handling, transparency, and the absence of adaptive immunity until 4–6 weeks. These factors allow… read more here.
Keywords: polymeric nps; drug loaded; model; loaded polymeric ... See more keywords
Rosmarinic Acid-Loaded Polymeric Nanoparticles Prepared by Low-Energy Nano-Emulsion Templating: Formulation, Biophysical Characterization, and In Vitro Studies
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15134572
Abstract: Rosmarinic acid (RA), a caffeic acid derivative, has been loaded in polymeric nanoparticles made up of poly(lactic-co-glycolic acid) (PLGA) through a nano-emulsion templating process using the phase-inversion composition (PIC) method at room temperature. The obtained… read more here.
Keywords: rosmarinic acid; polymeric nanoparticles; emulsion templating; nano emulsion ... See more keywords
Drug-Loaded Polymeric Particulated Systems for Ophthalmic Drugs Release
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27144512
Abstract: Drug delivery to the anterior or posterior segments of the eye is a major challenge due to the protection barriers and removal mechanisms associated with the unique anatomical and physiological nature of the ocular system.… read more here.
Keywords: systems ophthalmic; polymeric particulated; drug loaded; particulated systems ... See more keywords