Preclinical studies of the antitumor effect of curcumin‐loaded polymeric nanocapsules: A systematic review and meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7538
Abstract: Curcumin, a plant‐derived compound, has various well‐known biological effects (anti‐inflammatory, antioxidant, antitumor, among others) as well as some important limitations for formulators, such as poor water solubility and low oral bioavailability. Its nanoencapsulation is reported… read more here.
Keywords: polymeric nanocapsules; curcumin; curcumin loaded; systematic review ... See more keywords
Formulation and Characterization of Curcumin Loaded Polymeric Micelles Produced via Continuous Processing.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119340
Abstract: A continuous processing platform was developed to produce polymeric micelles. A block copolymer of mPEG (5kD)-PCL (2kD) was used as the model drug carrier. The polymeric micelles were produced using an innovative co-axial turbulent jet… read more here.
Keywords: continuous processing; loaded polymeric; curcumin loaded; drug ... See more keywords
Drug-loaded polymeric films as a promising tool for the treatment of periodontitis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.04.034
Abstract: Abstract This study addresses the fabrication and characterization of poly-caprolactone/alginic acid based drug-containing polymeric films. Two basic drugs used in the treatment of periodontal diseases (metronidazole and doxycycline) were investigated. The polymeric films were characterized… read more here.
Keywords: films promising; drug; treatment; polymeric films ... See more keywords
Evaluation of Pharmacokinetics, Biodistribution, and Antimalarial Efficacy of Artemether-Loaded Polymeric Nanorods.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00507
Abstract: Artemether oily injection is recommended for the treatment of severe malaria by the intramuscular route. The major limitations of the artemisinin combination therapy are erratic absorption from the injection site and high dosing frequency due… read more here.
Keywords: polymeric nanorods; artemether loaded; microscopy; pharmacokinetics biodistribution ... See more keywords
Synthesis and in vitro evaluation of natural drug loaded polymeric films for cardiovascular applications
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bioactive and Compatible Polymers"
DOI: 10.1177/08839115221085735
Abstract: Drug eluting stents (DES) can efficiently reduce the atherosclerosis and restenosis issues of coronary artery as compared to bare metal stents due to the presence of pharmaceutically active agent on their surface. Nevertheless, the arising… read more here.
Keywords: natural drug; polymeric films; drug loaded; synthesis vitro ... See more keywords
Zebrafish: A Useful Animal Model for the Characterization of Drug-Loaded Polymeric NPs
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10092252
Abstract: The use of zebrafish (ZF) embryos as an in vivo model is increasingly attractive thanks to different features that include easy handling, transparency, and the absence of adaptive immunity until 4–6 weeks. These factors allow… read more here.
Keywords: polymeric nps; drug loaded; model; loaded polymeric ... See more keywords
Rosmarinic Acid-Loaded Polymeric Nanoparticles Prepared by Low-Energy Nano-Emulsion Templating: Formulation, Biophysical Characterization, and In Vitro Studies
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15134572
Abstract: Rosmarinic acid (RA), a caffeic acid derivative, has been loaded in polymeric nanoparticles made up of poly(lactic-co-glycolic acid) (PLGA) through a nano-emulsion templating process using the phase-inversion composition (PIC) method at room temperature. The obtained… read more here.
Keywords: rosmarinic acid; polymeric nanoparticles; emulsion templating; nano emulsion ... See more keywords
Drug-Loaded Polymeric Particulated Systems for Ophthalmic Drugs Release
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27144512
Abstract: Drug delivery to the anterior or posterior segments of the eye is a major challenge due to the protection barriers and removal mechanisms associated with the unique anatomical and physiological nature of the ocular system.… read more here.
Keywords: systems ophthalmic; polymeric particulated; drug loaded; particulated systems ... See more keywords
Curcumin Loaded Polymeric vs. Lipid Nanoparticles: Antioxidant Effect on Normal and Hypoxic Olfactory Ensheathing Cells
Sign Up to like & getrecommendations! Published in 2021 at "Nanomaterials"
DOI: 10.3390/nano11010159
Abstract: Background: Curcumin (Cur) shows anti-inflammatory and antioxidant effects on central nervous system diseases. The aim of this study was to develop Cur-loaded polymeric and lipid nanoparticles for intranasal delivery to enhance its stability and increase… read more here.
Keywords: loaded polymeric; polymeric lipid; effect; cur ... See more keywords
Rapamycin-Loaded Polymeric Nanoparticles as an Advanced Formulation for Macrophage Targeting in Atherosclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13040503
Abstract: Recently, rapamycin (Rapa) represents a potential drug treatment to induce regression of atherosclerotic plaques; however, its use requires site-specific accumulation in the vessels involved in the formation of the plaques to avoid the systemic effects… read more here.
Keywords: rapa; loaded polymeric; polymeric nanoparticles; formulation ... See more keywords
Nanocomposite Cryogel Carriers from 2-Hydroxyethyl Cellulose Network and Cannabidiol-Loaded Polymeric Micelles for Sustained Topical Delivery
Sign Up to like & getrecommendations! Published in 2020 at "Polymers"
DOI: 10.3390/polym12051172
Abstract: In this contribution, we report the development of original nanocomposite cryogels for sustained topical delivery of hydrophobic natural active substances such as cannabidiol (CBD). The cryogels were fabricated by a method involving cryogenic treatment and… read more here.
Keywords: cryogel carriers; loaded polymeric; sustained topical; polymeric micelles ... See more keywords