Multicompartment Nanoparticles by Crystallization-Driven Self-Assembly of Star Polymers: Combining High Stability and Loading Capacity.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202200706
Abstract: Herein we develop a novel multicompartment nanoparticles (MCNs) that combine high stability and cargo loading capacity. The MCNs were fabricated by crystallization-driven self-assembly (CDSA) of a tailor-made 21 arm star polymer, poly(L -lactide)[poly(tert-buty acrylate)-block-poly(ethylene glycol)]20… read more here.
Keywords: high stability; capacity; loading capacity; crystallization driven ... See more keywords
Riboflavin-containing telodendrimer nanocarriers for efficient doxorubicin delivery: High loading capacity, increased stability, and improved anticancer efficacy.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2017.06.041
Abstract: We have developed two linear-dendritic telodendrimers (TDs) with rational design using amphiphilic riboflavin (Rf) as building blocks for efficient doxorubicin (DOX) delivery. Micellar TD nanoparticles (NPs) are composed of a hydrophilic polyethylene glycol (PEG) shell… read more here.
Keywords: loading capacity; delivery; efficient doxorubicin; dox ... See more keywords
CO2 loading capacity of DEA aqueous solutions: Modeling and assessment of experimental data
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Greenhouse Gas Control"
DOI: 10.1016/j.ijggc.2016.11.029
Abstract: Abstract In this communication, a mathematical approach on the basis of Leverage algorithm has been applied for evaluating the quality of experimental data of CO 2 loading capacity of DEA aqueous solutions as well as… read more here.
Keywords: aqueous solutions; experimental data; capacity dea; loading capacity ... See more keywords
A fast and reliable DSC‐based method to determine the monomolecular loading capacity of drugs with good glass‐forming ability in mesoporous silica
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.04.035
Abstract: Graphical abstract Figure. No Caption available. Abstract The aim of this study was to introduce a fast and reliable differential scanning calorimetry (DSC)‐based method to determine the monomolecular loading capacity of drugs with good glass‐forming… read more here.
Keywords: drug; glass; loading capacity; monomolecular loading ... See more keywords
Tryptophan-functionalized graphene quantum dots with enhanced curcumin loading capacity and pH-sensitive release
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102137
Abstract: Abstract Tryptophan-conjugated graphene quantum dots (Trp-GQDs) were fabricated for the first time and loaded with curcumin (Cur) as a hydrophobic anticancer agent, to evaluate Cur loading capacity and release kinetics, as well as its cytotoxicity… read more here.
Keywords: trp gqds; release; loading capacity; gqds ... See more keywords
Design of dual-responsive nanocarries with high drug loading capacity based on hollow mesoporous organosilica nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Materials Chemistry and Physics"
DOI: 10.1016/j.matchemphys.2019.05.025
Abstract: Abstract Pores and framework dual responsive controlled release systems with high drug loading capacity based on HMONs (DOX@HMONs/CD) have been prepared. The DOX@HMONs/CD show high loading capacity (1060 mg/g) for anticancer drug. The cumulative release of… read more here.
Keywords: drug; high drug; drug loading; capacity ... See more keywords
Combined loading capacity of skirted circular foundations in loose sand
Sign Up to like & getrecommendations! Published in 2019 at "Ocean Engineering"
DOI: 10.1016/j.oceaneng.2019.04.095
Abstract: Abstract Skirted foundations are an attractive foundation concept in the offshore energy sector, both for wind turbines and oil and gas platforms. Most of the evidence of skirted foundation behaviour under combined vertical, horizontal and… read more here.
Keywords: foundations loose; combined loading; capacity skirted; sand ... See more keywords
Engineering the Acoustic Response and Drug Loading Capacity of PBCA-Based Polymeric Microbubbles with Surfactants.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00416
Abstract: Gas-filled microbubbles (MB) are routinely used in the clinic as ultrasound contrast agents. MB are also increasingly explored as drug delivery vehicles based on their ultrasound stimuli-responsiveness and well-established shell functionalization routes. Broadening the range… read more here.
Keywords: loading capacity; pbca; drug; response ... See more keywords
Enhanced Drug Loading Capacity Using the Dual Metformine–Dexketoprofren Salt on Nanoapatite Materials
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.5c00264
Abstract: Both apatite nanoparticles and multicomponent pharmaceutical materials have proved the ability to significantly improve the bioavailability of different drugs using different strategies. Herein, the use of nanoapatite is proposed as a promising vehicle for advanced… read more here.
Keywords: drug loading; enhanced drug; drug; capacity using ... See more keywords
Glucose-Responsive Microneedle Patch with High Insulin Loading Capacity for Prolonged Glycemic Control in Mice and Minipigs.
Sign Up to like & getrecommendations! Published in 2024 at "ACS nano"
DOI: 10.1021/acsnano.4c05562
Abstract: Transdermal microneedle-mediated glucose-responsive insulin delivery systems can modulate insulin release based on fluctuations in blood glucose levels, thus maintaining normoglycemia effectively in a continuous, convenient, and minimally invasive manner. However, conventional microneedles are limited by… read more here.
Keywords: microneedle patch; glucose responsive; loading capacity; insulin ... See more keywords
Engineering of mRNA vaccine platform with reduced lipids and enhanced efficacy
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-63965-3
Abstract: Lipid nanoparticles (LNPs) are the most clinically relevant vehicles for mRNA vaccines. Despite the great successes, the toxicity caused by the high dose of lipid components still represents a great challenge. The suboptimal loading capacity… read more here.
Keywords: mrna vaccine; mrna; efficacy; loading capacity ... See more keywords