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   Articles with "lobaplatin" as a keyword



Lobaplatin induces pyroptosis through regulating cIAP1/2, Ripoptosome and ROS in nasopharyngeal carcinoma.

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recommendations! Published in 2020 at "Biochemical pharmacology"

DOI: 10.1016/j.bcp.2020.114023

Abstract: Cisplatin is the most commonly used chemotherapeutic drug for nasopharyngeal carcinoma (NPC), while its side effects are often intolerable. Lobaplatin, as an effective third-generation platinum with fewer adverse reactions and less platinum cross-resistance, has been… read more here.

Keywords: ciap1; cisplatin; lobaplatin; nasopharyngeal carcinoma ... See more keywords
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Single-nucleotide polymorphisms (rs342275, rs342293, rs7694379, rs11789898, and rs17824620) showed significant association with lobaplatin-induced thrombocytopenia.

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recommendations! Published in 2019 at "Gene"

DOI: 10.1016/j.gene.2019.143964

Abstract: This study aimed to investigate single-nucleotide polymorphisms (SNPs) associated with lobaplatin-induced thrombocytopenia in patients with advanced lung cancer in China. Thirty-nine patients who received lobaplatin-based chemotherapy in the 307 Hospitals of Chinese People's Liberation Army… read more here.

Keywords: lobaplatin induced; rs342275 rs342293; rs11789898 rs17824620; induced thrombocytopenia ... See more keywords
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Thoracic perfusion of lobaplatin combined with endostar for treating malignant pleural effusions: A meta-analysis and systematic review

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recommendations! Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000030749

Abstract: Introduction: Lobaplatin is a new platinum-based cytotoxic chemotherapeutic agent. Endostar is an endogenous angiogenic inhibitor with implicated anti-tumor activity. This study was to investigate the efficacy and safety of thoracic perfusion of lobaplatin combined with… read more here.

Keywords: lobaplatin combined; thoracic perfusion; odds ratio; lobaplatin ... See more keywords

Lobaplatin induces pyroptosis in cervical cancer cells via caspase-3/GSDME pathway.

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recommendations! Published in 2021 at "Anti-cancer agents in medicinal chemistry"

DOI: 10.2174/1871520621666211018100532

Abstract: BACKGROUND Increasing evidence shows that GSDME is involved in tumor chemotherapy. Lobaplatin is an important chemotherapy drug for the treatment of cervical cancer. However, the exact mechanism of lobaplatin in the treatment of cervical cancer… read more here.

Keywords: caspase; pyroptosis; gsdme; cervical cancer ... See more keywords

The Efficacy and Toxicity of Lobaplatin-contained Chemotherapy in Extensive-stage Small-cell Lung Cancer

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recommendations! Published in 2018 at "Journal of Cancer"

DOI: 10.7150/jca.24557

Abstract: To assess the efficacy and toxicity of Lobaplatin (LBP) -contained chemotherapy on extensive stage small-cell lung cancer (ES-SCLC), we conducted a prospective, single-arm, and multicenter Phase IV clinical trial on Lobaplatin (ChiCTR-ONC-13003471), and used the… read more here.

Keywords: contained chemotherapy; extensive stage; lobaplatin; cancer ... See more keywords