Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin
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DOI: 10.1155/2020/4258156
Abstract: Puerarin is the main biologically active isoflavone in Pueraria lobata and has a wide range of biological activities. However, due to its poor water solubility and low oral bioavailability, its clinical applications are restricted. Compared… read more here.
Keywords: pure puerarin; plasma; puerarin; lobata extract ... See more keywords
Pueraria lobata extract ameliorates D-GalN/LPS-induced liver injury through targeting TLR4/NF-κB signalling pathway and regulating gut microbiota
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DOI: 10.1556/066.2024.00173
Abstract: Kudzu root (Pueraria lobata), known for its dual role as a medicinal herb and food ingredient, has proven anti-inflammatory and antioxidant properties. This study explored the effects of P. lobata extract (PLE) on D-galactose/lipopolysaccharide (D-GalN/LPS)-induced… read more here.
Keywords: gut microbiota; galn lps; pueraria lobata; lps induced ... See more keywords
The Positive Influence of Polyphenols Extracted From Pueraria lobata Root on the Gut Microbiota and Its Antioxidant Capability
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DOI: 10.3389/fnut.2022.868188
Abstract: Pueraria lobata, an edible food and medicinal plant, is a rich source of bioactive components. In this study, a polyphenol-rich extract was isolated from P. lobata. Puerarin was identified, and the high antioxidant bioactivity of… read more here.
Keywords: gut microbiota; positive influence; pueraria lobata; lobata extract ... See more keywords