Comment on article by Zhong et al.: Local administration of epsilon-aminocaproic acid reduces post-operative blood loss from surgery for closed, Sanders III–IV calcaneal fractures
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DOI: 10.1007/s00264-022-05355-8
Abstract: It was with great interest that we read the paper by Zhong et al. [1] entitled “Local administration of epsilon-aminocaproic acid reduces post-operative blood loss from surgery for closed, Sanders III–IV calcaneal fractures” published online… read more here.
Keywords: group; blood loss; local administration; blood ... See more keywords
Effects of Local Administration of Tranexamic Acid on Reducing Postoperative Blood Loss in Surgeries for Closed, Sanders III–IV Calcaneal Fractures: A Randomized Controlled Study
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DOI: 10.1007/s43465-021-00417-2
Abstract: Purpose To investigate whether local administration of tranexamic acid (TXA) is effective in postoperative blood loss reduction in surgeries for Sanders III–IV calcaneal fractures. Methods Calcaneal fracture patients who were hospitalized in our hospital from… read more here.
Keywords: local administration; group group; postoperative blood; group ... See more keywords
Local Administration of Methylcobalamin for Subacute Ophthalmic Herpetic Neuralgia: A Randomized, Phase III Clinical Trial
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DOI: 10.1111/papr.12909
Abstract: The ophthalmic branch of the trigeminal nerve is one of the most frequently involved sites of postherpetic neuralgia. A single‐center randomized controlled study was conducted to evaluate the efficacy of local methylcobalamin injection for subacute… read more here.
Keywords: herpetic neuralgia; local administration; administration methylcobalamin; ophthalmic herpetic ... See more keywords
Local administration of mesenchymal stromal cells is safe and modulates the immune compartment in ulcerative proctitis.
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DOI: 10.1172/jci.insight.167402
Abstract: BACKGROUND Due to their immunoregulatory and tissue regenerative features, mesenchymal stromal cells (MSCs) are a promising novel tool for the management of ulcerative proctitis (UP). Here we report on a phase IIa clinical study to… read more here.
Keywords: mesenchymal stromal; local administration; week; immune compartment ... See more keywords
Local Administration of Ginkgolide B Using a Hyaluronan-Based Hydrogel Improves Wound Healing in Diabetic Mice
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DOI: 10.3389/fbioe.2022.898231
Abstract: The delayed and incomplete healing of diabetic wounds remains a major concern of global healthcare. The complex biological processes within the diabetic wound, such as chronic inflammation, impaired blood vessel growth and immature collagen remodeling,… read more here.
Keywords: healing diabetic; administration ginkgolide; diabetic mice; ginkgolide using ... See more keywords
Effects of Systemic or Local Administration of Mesenchymal Stem Cells from Patients with Osteoporosis or Osteoarthritis on Femoral Fracture Healing in a Mouse Model
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DOI: 10.3390/biom12050722
Abstract: The purpose of this study was to analyze the regenerative capacity of mesenchymal stem cells (MSCs) in the treatment of fractures. MSCs extracted from patients with osteoporotic hip fractures or hip osteoarthritis undergoing hip replacement… read more here.
Keywords: fracture; osteoporosis osteoarthritis; administration; patients osteoporosis ... See more keywords
Local Administration of ElectroMagnetic Field as Add-On Therapy in the Treatment of Chronic Facial Pain: A Pilot Study
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DOI: 10.3390/ijerph19074123
Abstract: Fibromyalgic syndrome and orofacial neuropathic pain are major public health concerns affecting up to 5% and 10%, respectively, of the general population. They generally require medications such as antidepressants and anticonvulsants, which may additionally impact… read more here.
Keywords: pain; administration electromagnetic; local administration; neuropathic pain ... See more keywords
Pulmonary Pharmacokinetics of Antibody and Antibody Fragments Following Systemic and Local Administration in Mice
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DOI: 10.3390/pharmaceutics16101259
Abstract: Objective: This study aimed to investigate the effect of molecular size on the pulmonary pharmacokinetics (PK) of proteins following systemic and local administration in wild-type mice. Methods: A non-cross-reactive antibody trastuzumab, and F(ab′)2, Fab, and… read more here.
Keywords: pulmonary pharmacokinetics; following systemic; antibody; systemic local ... See more keywords
Recent Advances in Methods for Local Administration of Drugs around Dental Implants
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DOI: 10.4103/jioh.jioh_174_24
Abstract: The release of therapeutic agents directly at a dental implant site may offer low but effective doses of drugs compared to conventional methods. This study aimed to investigate recent advances in the methods for local… read more here.
Keywords: methods local; local administration; drug; recent advances ... See more keywords