Dextromethorphan - A widely-used cough suppressant - Induces local anaphylaxis via MRGPRX2 on mast cells.
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DOI: 10.1016/j.cbi.2020.109248
Abstract: Dextromethorphan (DM) is a cough suppressant available in many prescribed and over-the-counter medications. Adverse reactions induced by DM have been regularly reported, including allergic skin reactions in some cases. However, the underlying mechanisms of local… read more here.
Keywords: mrgprx2; mast cells; mast; via mrgprx2 ... See more keywords