A fast Data-Driven method for genotype imputation, phasing, and local ancestry inference: MendelImpute.jl.
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab489
Abstract: MOTIVATION Current methods for genotype imputation and phasing exploit the volume of data in haplotype reference panels and rely on hidden Markov models. Existing programs all have essentially the same imputation accuracy, are computationally intensive,… read more here.
Keywords: genotype imputation; imputation phasing; mendelimpute; method genotype ... See more keywords
Genomic consequences of a recent three‐way admixture in supplemented wild brown trout populations revealed by local ancestry tracts
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Ecology"
DOI: 10.1111/mec.14816
Abstract: Understanding the evolutionary consequences of human‐mediated introductions of domesticated strains into the wild and their subsequent admixture with natural populations is of major concern in conservation biology. However, the genomic impacts of stocking from distinct… read more here.
Keywords: brown trout; admixture; admixture supplemented; domestic strains ... See more keywords
The Role of Global and Local Ancestry on Clopidogrel Response in African Americans
Sign Up to like & getrecommendations! Published in 2022 at "Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing"
DOI: 10.1142/9789811270611_0021
Abstract: Pharmacogenomics has long lacked dedicated studies in African Americans, resulting in a lack of in-depth data in this populations. The ACCOuNT consortium has collected a cohort of 167 African American patients on steady state clopidogrel… read more here.
Keywords: local ancestry; ancestry; african americans; role global ... See more keywords
Haplotypes of single cancer driver genes and their local ancestry in a highly admixed long-lived population of Northeast Brazil
Sign Up to like & getrecommendations! Published in 2022 at "Genetics and Molecular Biology"
DOI: 10.1590/1678-4685-gmb-2021-0172
Abstract: Abstract Admixed populations have not been examined in detail in cancer genetic studies. Here, we inferred the local ancestry of cancer-associated single nucleotide polymorphisms (SNPs) and haplotypes of a highly admixed Brazilian population. SNP array… read more here.
Keywords: local ancestry; ancestry; highly admixed; cancer driver ... See more keywords