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   Articles with "local assembly" as a keyword



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novoBreak: local assembly for breakpoint detection in cancer genomes

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recommendations! Published in 2017 at "Nature methods"

DOI: 10.1038/nmeth.4084

Abstract: We present novoBreak, a genome-wide local assembly algorithm that discovers somatic and germline structural variation breakpoints in whole-genome sequencing data. novoBreak consistently outperformed existing algorithms on real cancer genome data and on synthetic tumors in… read more here.

Keywords: assembly; local assembly; assembly breakpoint; novobreak local ... See more keywords
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A pipeline for local assembly of minisatellite alleles from single-molecule sequencing data

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recommendations! Published in 2017 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btw687

Abstract: Motivation: The advent of Next Generation Sequencing (NGS) has led to the generation of enormous volumes of short read sequence data, cheaply and in reasonable time scales. Nevertheless, the quality of genome assemblies generated using… read more here.

Keywords: molecule; molecule sequencing; single molecule; pipeline ... See more keywords
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Role of local assembly in the hierarchical crystallization of associating colloidal hard hemispheres

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recommendations! Published in 2017 at "Physical Review Materials"

DOI: 10.1103/physrevmaterials.1.052601

Abstract: Hierarchical self-assembly consisting of local associations of simple building-blocks for the formation of complex structures widely exists in nature, while the essential role of local assembly remains unknown. In this work, by using computer simulations,… read more here.

Keywords: hierarchical crystallization; role local; crystallization; local assembly ... See more keywords
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SLAG: A Program for Seeded Local Assembly of Genes in Complex Genomes.

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recommendations! Published in 2022 at "Molecular ecology resources"

DOI: 10.1111/1755-0998.13580

Abstract: Although finished genomes have become more common, there is still a need for assemblies of individual genes or chromosomal regions when only unassembled reads are available. SLAG (Seeded Local Assembly of Genes) fulfills this need… read more here.

Keywords: slag; assembly genes; seeded local; assembly ... See more keywords