Mechanosensitivity of microdomain calcium signalling in the heart.
Sign Up to like & getrecommendations! Published in 2017 at "Progress in biophysics and molecular biology"
DOI: 10.1016/j.pbiomolbio.2017.06.013
Abstract: In cardiac myocytes, calcium (Ca2+) signalling is tightly controlled in dedicated microdomains. At the dyad, i.e. the narrow cleft between t-tubules and junctional sarcoplasmic reticulum (SR), many signalling pathways combine to control Ca2+-induced Ca2+ release… read more here.
Keywords: mechanosensitivity; microdomain calcium; local ca2; mechanosensitivity microdomain ... See more keywords
Computer algorithms for automated detection and analysis of local Ca2+ releases in spontaneously beating cardiac pacemaker cells
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179419
Abstract: Local Ca2+ Releases (LCRs) are crucial events involved in cardiac pacemaker cell function. However, specific algorithms for automatic LCR detection and analysis have not been developed in live, spontaneously beating pacemaker cells. In the present… read more here.
Keywords: cardiac pacemaker; pacemaker; local ca2; ca2 releases ... See more keywords