A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.06.048
Abstract: During neuronal development, local mRNA translation is required for axon guidance and synaptogenesis, and dysregulation of this process contributes to multiple neurodevelopmental and cognitive disorders. However, regulation of local protein synthesis in developing axons remains poorly… read more here.
Keywords: actin; mena; mrna translation; translation ... See more keywords
Local mRNA translation and cytoskeletal reorganization: Mechanisms that tune neuronal responses
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.949096
Abstract: Neurons are highly polarized cells with significantly long axonal and dendritic extensions that can reach distances up to hundreds of centimeters away from the cell bodies in higher vertebrates. Their successful formation, maintenance, and proper… read more here.
Keywords: mrna translation; local mrna; translation cytoskeletal; translation ... See more keywords