Monitoring Protein Global and Local Parameters in Unfolding and Binding Studies: The Extended Applicability of the Diffusion Coefficient─Molecular Size Empirical Relations.
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DOI: 10.1021/acs.analchem.2c00481
Abstract: Protein unfolding and denaturation are main issues in biochemical and pharmaceutical research. Using a global parameter, the translational diffusion coefficient D, folded, unfolded, and intrinsically disordered proteins of a given molar mass M can be… read more here.
Keywords: local parameters; diffusion; empirical relations; diffusion coefficient ... See more keywords