Engineered Hydrogels for Local and Sustained Delivery of RNA-Interference Therapies.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201601041
Abstract: It has been nearly two decades since RNA-interference (RNAi) was first reported. While there are no approved clinical uses, several phase II and III clinical trials suggest the great promise of RNAi therapeutics. One challenge… read more here.
Keywords: local sustained; hydrogels local; rna interference; rnai ... See more keywords
Prospective Evaluation of Local Sustained Release of Celecoxib in Dogs with Low Back Pain
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13081178
Abstract: Back pain affects millions globally and in 40% of the cases is attributed to intervertebral disc degeneration. Oral analgesics are associated with adverse systemic side-effects and insufficient pain relief. Local drug delivery mitigates systemic effects… read more here.
Keywords: local sustained; evaluation local; back pain; prospective evaluation ... See more keywords
In Situ-Forming Gels Loaded with Stimuli-Responsive Gated Mesoporous Silica Nanoparticles for Local Sustained Drug Delivery
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DOI: 10.3390/pharmaceutics15041071
Abstract: A novel combination of in situ-forming hydrogels of hyaluronic acid with gated mesoporous materials was developed to design depots for local sustained release of chemotherapeutics. The depot consists of a hyaluronic-based gel loaded with redox-responsive… read more here.
Keywords: silica nanoparticles; mesoporous silica; situ forming; gated mesoporous ... See more keywords