Local and Targeted Delivery of Immune Checkpoint Blockade Therapeutics.
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DOI: 10.1021/acs.accounts.0c00339
Abstract: ConspectusImmune checkpoint blockade (ICB) therapy elicits antitumor response by inhibiting immune suppressor components, including programmed cell death protein 1 and its ligand (PD-1/PD-L1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). Despite improved therapeutic efficacy, the clinical… read more here.
Keywords: checkpoint blockade; icb; local targeted; delivery ... See more keywords