Definitive local therapy to head and neck squamous cell carcinoma with distant metastasis
Sign Up to like & getrecommendations! Published in 2022 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.807
Abstract: Data on the efficacy of including definitive local therapy to the primary site for head and neck squamous cell carcinoma (HNSCC) patients with synchronous distant metastasis are lacking. In multiple different solid tumor types, there… read more here.
Keywords: head neck; local therapy; squamous cell; therapy ... See more keywords
The Emerging Role of Local Therapy in Metastatic Prostate Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Current Oncology Reports"
DOI: 10.1007/s11912-020-0868-1
Abstract: Purpose of Review This review summarizes the prospective clinical evidence regarding local therapy in metastatic prostate cancer. Recent Findings The phase 3 STAMPEDE trial showed that prostate radiotherapy confers a survival benefit for newly diagnosed… read more here.
Keywords: prostate; therapy metastatic; local therapy; prostate cancer ... See more keywords
P3.01-65 First-Line Radical Local Therapy May Provide Additional Survival Gain for Patients with EGFR-Mutant Metastatic NSCLC Receiving TKIs
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thoracic Oncology"
DOI: 10.1016/j.jtho.2018.08.1625
Abstract: as different line therapies. The disease control rate of chemotherapy, immunotherapy, MKI group was 70.0%, 71.43% and 50%, respectively. While the median PFS of three groups was 2.50 months, 2.70 months, 0.30 months, respectively, which… read more here.
Keywords: line; first line; therapy may; line radical ... See more keywords
Yes or no to local therapy for oligometastatic prostate cancer?
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Urology"
DOI: 10.1038/s41585-018-0028-7
Abstract: Metastatic prostate cancer has traditionally been treated with systemic therapy alone, but the issue of oligometastatic disease raises the question of whether local therapy — radical prostatectomy or prostate radiotherapy — should be performed. A… read more here.
Keywords: prostate; yes local; prostate cancer; local therapy ... See more keywords
Prognostic impact of prior local therapy in castration-resistant prostate cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyab019
Abstract: OBJECTIVE This study aimed to reveal the prognostic values of prior local therapy in first-line therapy using androgen receptor-axis targeting agents (abiraterone or enzalutamide) or docetaxel for castration-resistant prostate cancer (CRPC). METHODS The study included… read more here.
Keywords: prostate cancer; prior local; local therapy; castration resistant ... See more keywords
Is radical local therapy effective in postoperative recurrent EGFR-mutated non-small cell lung cancer?
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14911
Abstract: BACKGROUND Long-term survival can be achieved with radical local therapy in some cases of postoperative recurrence of non-small cell lung cancer (NSCLC). Here, we evaluated post-recurrence survival (PRS) after treatment of postoperative recurrent epidermal growth… read more here.
Keywords: survival; local therapy; recurrence; radical local ... See more keywords
Definitive local therapy for T4 prostate cancer associated with improved local control and survival.
Sign Up to like & getrecommendations! Published in 2023 at "BJU international"
DOI: 10.1111/bju.16027
Abstract: OBJECTIVES To evaluate clinical (c)T4 prostate cancer patients, which represent both a heterogenous and understudied population, who often present with locally advanced disease and obstructive symptoms causing significant morbidity and mortality. We analyzed whether receiving… read more here.
Keywords: prostate cancer; disease; local therapy; therapy ... See more keywords
Local therapy for cancer therapy-associated uveitis: a case series and review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Ophthalmology"
DOI: 10.1136/bjophthalmol-2019-314403
Abstract: Background/aims Immunotherapy and targeted therapy for metastatic cancer may cause immune-related adverse events (irAEs) such as uveitis. If irAEs are severe or require systemic steroids, cancer therapy is often held or discontinued. Local steroid therapy… read more here.
Keywords: associated uveitis; therapy associated; local therapy; cancer ... See more keywords
Management of patients with brain metastases from NSCLC without a genetic driver alteration: upfront radiotherapy or immunotherapy?
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359231175438
Abstract: Lung cancer is the second most common cancer and the most common cause of cancer-related death in the United States. Brain metastases (BM) are detected in 21% of patients with lung cancer at the time… read more here.
Keywords: brain metastases; local therapy; alteration; therapy ... See more keywords
Local Option: The Rational Use of Local Therapy in Patients at High Risk to Die of Metastatic Progression.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of oncology practice"
DOI: 10.1200/jop.17.00052
Abstract: On occasion, clinicians may be motivated to offer local therapy (eg, surgery, radiation, ablation) to patients with advanced cancer in the hope of prolonging survival (as opposed to palliating a symptom). An appropriately informed discussion… read more here.
Keywords: use local; local therapy; therapy; progression ... See more keywords
Role of local therapy in the management of patients with metastatic anal squamous cell carcinoma: a National Cancer Database study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-125
Abstract: Background About 10–20% of patients with anal squamous cell carcinoma (SCCa) present with metastatic disease and are usually treated with systemic chemotherapy. However, primary tumor control is crucial as local failure is associated with significant… read more here.
Keywords: cell carcinoma; anal squamous; local therapy; squamous cell ... See more keywords