Right place, right time: localisation and assembly of the NLRP3 inflammasome
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DOI: 10.12688/f1000research.18557.1
Abstract: The NLRP3 inflammasome is a multimeric protein complex that cleaves caspase-1 and the pro-inflammatory cytokines interleukin 1 beta (IL-1β) and IL-18. Dysregulated NLRP3 inflammasome signalling is linked to several chronic inflammatory and autoimmune conditions; thus,… read more here.
Keywords: inflammasome; localisation assembly; right place; nlrp3 inflammasome ... See more keywords