Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4
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DOI: 10.3390/cancers11091349
Abstract: Estrogen activity towards cancer-related pathways can impact therapeutic intervention. Recent omics data suggest possible crosstalk between estrogens/gender and MDM4, a key regulator of p53. Since MDM4 can either promote cell transformation or enhance DNA damage-sensitivity,… read more here.
Keywords: mdm4; estrogen; estrogens counteract; sensitivity ... See more keywords