Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1.
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DOI: 10.1016/j.bbrc.2017.07.107
Abstract: GLI1 is a key downstream transcription effector of the Hedgehog (Hh) signaling pathway that is involved in promoting cell growth, differentiation and tissue patterning in embryonic development. GLI1 over-activation and its nuclear localization has also… read more here.
Keywords: localization sequence; nuclear localization; gli1; site ... See more keywords