Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells.
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DOI: 10.2139/ssrn.4144958
Abstract: Reactive oxygen species (ROS) can modulate protein function through cysteine oxidation. Identifying protein targets of ROS can provide insight into uncharacterized ROS-regulated pathways. Several redox-proteomic workflows, such as oxidative isotope-coded affinity tags (OxICAT), exist to… read more here.
Keywords: cysteine oxidation; oxidation; localized cysteine; oxidation events ... See more keywords