Abstract 1466: DAXX localizes ATRX to suppress alternative lengthening of telomeres in osteosarcoma
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DOI: 10.1158/1538-7445.am2018-1466
Abstract: To maintain genome stability, proliferating cells must add telomere sequence to counteract the chromosome end replication problem. In normal cells, telomeres are lengthened through the action of the enzyme telomerase. In about 10-15% of tumors,… read more here.
Keywords: daxx localizes; daxx; alternative lengthening; localizes atrx ... See more keywords