Nir1 constitutively localizes at ER–PM junctions and promotes Nir2 recruitment for PIP2 homeostasis
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DOI: 10.1091/mbc.e21-07-0356
Abstract: Homeostatic regulation of plasma membrane (PM) phosphatidylinositol 4,5-bisphosphate (PIP2) in receptor-stimulated cells is mediated by the lipid transfer protein Nir2. Nir2 is dynamically recruited to endoplasmic reticulum–plasma membrane (ER–PM) junctions to facilitate replenishment of PM… read more here.
Keywords: constitutively localizes; pip2 homeostasis; localizes junctions; pip2 ... See more keywords