Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2100514
Abstract: Abstract It was found that propranolol hydrochloride (PNL), which is a beta-blocker used for hypertension treatment, has a potent spermicidal activity through local anesthetic activity or beta-blocking effect on sperm cells subsequently it could be… read more here.
Keywords: vivo; invs; locally acting; acting contraceptive ... See more keywords
Editorial: Delivery of Locally-Acting Agents to Intracellular Targets
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.593064
Abstract: The vast majority of pharmaceuticals penetrate into tissues and cells regardless of their actual requirements for treatment. This leads to side effects, which restrict the use of drugs and require decrease of the treatment doses.… read more here.
Keywords: research; delivery; target; pharmacology ... See more keywords