Location, Location, Location: EphB4:Ephrin-B2 Signaling Depends on Its Spatial Arrangement.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical journal"
DOI: 10.1016/j.bpj.2018.07.014
Abstract: Cells have a challenge in crowded environments. They need to send specific messages to their nearest neighbors but not to cells two or three doorsteps away. This is a common problem in cell-to-cell communication that… read more here.
Keywords: location; ephb4 ephrin; location ephb4; ephrin signaling ... See more keywords
Location, location, location: nuclear structure regulates gene expression in neurons
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2019.03.009
Abstract: Genome architecture plays a critical role in regulating the expression of genes that are essential for nervous system development. During neuronal differentiation, spatially and temporally regulated transcription allows neuronal migration, the growth of dendrites and… read more here.
Keywords: location; location nuclear; location location; nuclear structure ... See more keywords
Location, Location, Location - Does Epitope Matching Matter in Pediatric Heart Transplantation?
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.376
Abstract: Purpose Recent data in adult solid organ transplantation suggest that epitope-based human leukocyte antigen (HLA) matching may permit better risk assessment of de novo donor‐specific antibody (dnDSA) development compared to antigen-based HLA matching, but data… read more here.
Keywords: number; location; epitope; epitope mismatches ... See more keywords
Location, location, location: Examining the rural-urban skills gap in Canada
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Rural Studies"
DOI: 10.1016/j.jrurstud.2019.10.032
Abstract: Abstract The elevated demands of the new knowledge economy pose particular challenges to rural and northern regions in Canada, long acknowledged by policymakers to suffer from acute human capital deficits. Rural residents obtain lower levels… read more here.
Keywords: rural urban; location; urban skills; examining rural ... See more keywords
Dissecting Gene Repression: Not Just Location, Location, Location.
Sign Up to like & getrecommendations! Published in 2019 at "Trends in cell biology"
DOI: 10.1016/j.tcb.2019.06.001
Abstract: Large heterochromatic domains are found tethered to the lamina. But, is this nuclear environment repressive per se, or just the 'ground state' of inactive chromatin? Elegant studies from the van Steensel group (Leemans et al.,… read more here.
Keywords: dissecting gene; location; gene repression; repression location ... See more keywords
Location, Location, Location: Compartmentalization of NAD+ Synthesis and Functions in Mammalian Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Trends in biochemical sciences"
DOI: 10.1016/j.tibs.2020.05.010
Abstract: The numerous biological roles of NAD+ are organized and coordinated via its compartmentalization within cells. The spatial and temporal partitioning of this intermediary metabolite is intrinsic to understanding the impact of NAD+ on cellular signaling… read more here.
Keywords: location compartmentalization; location location; location; nad synthesis ... See more keywords
Location, location, location: how the tissue microenvironment affects inflammation in RA
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-020-00570-2
Abstract: Current treatments for rheumatoid arthritis (RA) do not work well for a large proportion of patients, or at all in some individuals, and cannot cure or prevent this disease. One major obstacle to developing better… read more here.
Keywords: inflammation; disease; tissue; location location ... See more keywords
Location, location, and activation of a channel by calcium
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2214826119
Abstract: Calcium’s importance in signaling has been known since Ringer showed that it was needed for contraction of isolated hearts in 1883. Calcium remained a curiosity until the mid 1940s when Heilbrunn showed that intracellular calcium… read more here.
Keywords: cell; calcium; location; location location ... See more keywords
Location, Location, Location: The Variable Value of Renewable Energy and Demand-Side Efficiency Resources
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Association of Environmental and Resource Economists"
DOI: 10.1086/694179
Abstract: Greenhouse gas mitigation efforts in the electricity sector have emphasized accelerated deployment of energy efficiency (EE) measures and renewable energy (RE) resources. We evaluate renewable energy and energy efficiency technologies across regional power systems in… read more here.
Keywords: location; energy; renewable energy; location location ... See more keywords
Location, location, location: does providing public health services from community pharmacies contribute to tackling health inequalities?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of public health"
DOI: 10.1093/pubmed/fdac148
Abstract: BACKGROUND Community pharmacies have long been advocated as an accessible source of advice on health improvement in communities. This cross-sectional study explored the association between provision of pharmacy public health services and factors that might… read more here.
Keywords: health; public health; community pharmacies; location location ... See more keywords
Location, location, location: survival of Antarctic biota requires the best real estate
Sign Up to like & getrecommendations! Published in 2023 at "Biology Letters"
DOI: 10.1098/rsbl.2022.0590
Abstract: The origin of terrestrial biota in Antarctica has been debated since the discovery of springtails on the first historic voyages to the southern continent more than 120 years ago. A plausible explanation for the long-term… read more here.
Keywords: location; location location; location survival; antarctic biota ... See more keywords