Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2022.0891
Abstract: Importance Keratoconus can be a debilitating corneal ectasia in which the cornea thins, bulges, and steepens into a conical shape. Early features of keratoconus include myopia and irregular astigmatism, which affect vision and can be… read more here.
Keywords: loci; crf; keratoconus; cct ... See more keywords
Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2023.0706
Abstract: Importance Central serous chorioretinopathy (CSC) is a serous maculopathy of unknown etiology. Two of 3 previously reported CSC genetic risk loci are also associated with AMD. Improved understanding of CSC genetics may broaden our understanding… read more here.
Keywords: csc; loci; serous chorioretinopathy; risk ... See more keywords
Elevated diversity in loci linked to facial morphology is consistent with the hypothesis that individual facial recognition is important across hominoids.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of physical anthropology"
DOI: 10.1002/ajpa.24233
Abstract: OBJECTIVES The ability to use visual signals to identify individuals is an important feature of primate social groups, including humans. Sheehan and Nachman (2014) showed that loci linked to facial morphology had elevated levels of… read more here.
Keywords: loci; loci linked; diversity; facial morphology ... See more keywords
Development and characterization of 30 microsatellite loci for Plagiorhegma dubium (Berberidaceae)
Sign Up to like & getrecommendations! Published in 2018 at "Applications in Plant Sciences"
DOI: 10.1002/aps3.1200
Abstract: Premise of the Study Plagiorhegma dubium (Berberidaceae) has been listed as an endangered species in Korea due to extensive collection and destruction of natural habitats. In this study, 30 microsatellite loci, including 25 polymorphic loci,… read more here.
Keywords: dubium; loci; plagiorhegma dubium; dubium berberidaceae ... See more keywords
DNA methylation and obesity in survivors of pediatric acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1002/gcc.22701
Abstract: Because survivors of pediatric acute lymphoblastic leukemia (ALL) are more likely to be obese than unaffected contemporaries, we compared DNA methylation profiles between normal‐weight and obese survivors at adiposity‐associated CpG sites previously‐reported by epigenome‐wide association… read more here.
Keywords: loci; survivors pediatric; obesity survivors; obesity ... See more keywords
Genome‐wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32698
Abstract: Genome‐wide association studies (GWAS) have identified 45 susceptibility loci associated with lung cancer. Only less than SNPs, small insertions and deletions (INDELs) are the second most abundant genetic polymorphisms in the human genome. INDELs are… read more here.
Keywords: cancer; cancer risk; loci; lung cancer ... See more keywords
Integration of Multi-omics Data for Expression Quantitative Trait Loci (eQTL) Analysis and eQTL Epistasis.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0026-9_11
Abstract: Expression quantitative trait loci (eQTL) mapping studies identify genetic loci that regulate gene expression. eQTL mapping studies can capture gene regulatory interactions and provide insight into the genetic mechanism of biological systems. Recently, the integration… read more here.
Keywords: loci; multi omics; omics data; eqtl ... See more keywords
Pleiotropic loci underlying bone mineral density and bone size identified by a bivariate genome-wide association analysis
Sign Up to like & getrecommendations! Published in 2020 at "Osteoporosis International"
DOI: 10.1007/s00198-020-05389-x
Abstract: Aiming to identify pleiotropic genomic loci for bone mineral density and bone size, we performed a bivariate GWAS in five discovery samples and replicated in two large-scale samples. We identified 2 novel loci at 2q37.1… read more here.
Keywords: loci; bone size; genome wide; bone mineral ... See more keywords
Genetic variation for three Y-STR loci: DYS390, DYS518, and DYS643
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-018-1947-9
Abstract: Y chromosome short tandem repeats (Y-STRs) are commonly used to analyze male-specific DNA. Although biallelic patterns due to duplication events have been detected at some loci, Y-STRs generally appear as a single peak except for… read more here.
Keywords: loci; variation; dys518 dys643; dys390 dys518 ... See more keywords
Development and characterization of 15 novel polymorphic microsatellite loci for two important bot flies (Diptera, Oestridae) by next-generation sequencing
Sign Up to like & getrecommendations! Published in 2020 at "Parasitology Research"
DOI: 10.1007/s00436-020-06824-y
Abstract: Cephenemyia stimulator and Oestrus ovis are two important parasitic bot flies (Oestridae) species causing myiasis, with a potential negative impact on the welfare of the host. Using next-generation sequencing approach and bioinformatics tools, a large… read more here.
Keywords: loci; bot flies; microsatellite loci; next generation ... See more keywords
Development and characterization of 12 polymorphic microsatellite loci in the sea sandwort, Honckenya peploides
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Plant Research"
DOI: 10.1007/s10265-018-1036-7
Abstract: Codominant marker systems are better suited to analyze population structure and assess the source of an individual in admixture analyses. Currently, there is no codominant marker system using microsatellites developed for the sea sandwort, Honckenya… read more here.
Keywords: loci; honckenya peploides; sea sandwort; microsatellite loci ... See more keywords