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Published in 2022 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-021-00579-4
Abstract: We previously demonstrated the efficacy of a frozen dalbavancin–heparin (DH) lock solution against biofilms of staphylococci. However, as enterococci also commonly cause catheter-related bloodstream infections (C-RBSI), we assessed the bioactivity of frozen dalbavancin (D) and…
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Keywords:
lock solution;
solution;
dalbavancin lock;
enterococcal biofilms ... See more keywords
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Published in 2021 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c06427
Abstract: Antimicrobial-lock therapy is an economically viable strategy to prevent/reduce the catheter-related bloodstream infections (CRBSI) that are associated with central venous catheters (CVCs). Herein, we report the synthesis and characterization of the S-nitroso-N-acetyl-l-cysteine ethyl ester (SNACET),…
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Keywords:
lock;
catheter;
lock solution;
snacet lock ... See more keywords
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Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1756
Abstract: Abstract Background Blood stream infections due to Candida auris is a significant public health concern due to increased patient mortality, frequent misidentification, and high rates of antifungal resistance. C. auris is known to be azole…
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Keywords:
lock;
speaker honorarium;
auris biofilms;
speaker ... See more keywords
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1
Published in 2018 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.000749
Abstract: Purpose. The new lipoglycopeptide dalbavancin has only been approved for acute bacterial skin and skin structure infections. However, its alternative use as a catheter lock solution could facilitate the conservative management of catheter‐related bloodstream infection.…
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Keywords:
combination;
catheter;
solution;
lock solution ... See more keywords
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Published in 2018 at "mSphere"
DOI: 10.1128/msphere.00525-18
Abstract: The colonization of catheters by microorganisms often precludes their long-term use, which can be a problem for human patients that have few body sites available for new catheters. The colonizing organisms often form biofilms, and…
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Keywords:
lock solution;
edta effective;
use;
tetrasodium edta ... See more keywords
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Published in 2025 at "Antibiotics"
DOI: 10.3390/antibiotics14060605
Abstract: Background/Objectives: Vancomycin (V) is widely used for catheter lock therapy. However, its ad hoc preparation in pharmacy departments involves discarding most of an intravenous vial and contributes to high workload. We aimed to assess the…
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Keywords:
concentration;
solution;
catheter lock;
lock solution ... See more keywords