Articles with "lock solution" as a keyword



A Dalbavancin Lock Solution Can Reduce Enterococcal Biofilms After Freezing

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Published in 2022 at "Infectious Diseases and Therapy"

DOI: 10.1007/s40121-021-00579-4

Abstract: We previously demonstrated the efficacy of a frozen dalbavancin–heparin (DH) lock solution against biofilms of staphylococci. However, as enterococci also commonly cause catheter-related bloodstream infections (C-RBSI), we assessed the bioactivity of frozen dalbavancin (D) and… read more here.

Keywords: lock solution; solution; dalbavancin lock; enterococcal biofilms ... See more keywords

S-Nitroso-N-acetyl-l-cysteine Ethyl Ester (SNACET) Catheter Lock Solution to Reduce Catheter-Associated Infections.

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Published in 2021 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.1c06427

Abstract: Antimicrobial-lock therapy is an economically viable strategy to prevent/reduce the catheter-related bloodstream infections (CRBSI) that are associated with central venous catheters (CVCs). Herein, we report the synthesis and characterization of the S-nitroso-N-acetyl-l-cysteine ethyl ester (SNACET),… read more here.

Keywords: lock; catheter; lock solution; snacet lock ... See more keywords

2100. Nitroglycerin-Citrate-Ethanol Catheter Lock Solution Is Highly Effective in Eradicating Candida auris Biofilms

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Published in 2018 at "Open Forum Infectious Diseases"

DOI: 10.1093/ofid/ofy210.1756

Abstract: Abstract Background Blood stream infections due to Candida auris is a significant public health concern due to increased patient mortality, frequent misidentification, and high rates of antifungal resistance. C. auris is known to be azole… read more here.

Keywords: lock; speaker honorarium; auris biofilms; speaker ... See more keywords

Can dalbavancin be used as a catheter lock solution?

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Published in 2018 at "Journal of Medical Microbiology"

DOI: 10.1099/jmm.0.000749

Abstract: Purpose. The new lipoglycopeptide dalbavancin has only been approved for acute bacterial skin and skin structure infections. However, its alternative use as a catheter lock solution could facilitate the conservative management of catheter‐related bloodstream infection.… read more here.

Keywords: combination; catheter; solution; lock solution ... See more keywords

Tetrasodium EDTA Is Effective at Eradicating Biofilms Formed by Clinically Relevant Microorganisms from Patients’ Central Venous Catheters

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Published in 2018 at "mSphere"

DOI: 10.1128/msphere.00525-18

Abstract: The colonization of catheters by microorganisms often precludes their long-term use, which can be a problem for human patients that have few body sites available for new catheters. The colonizing organisms often form biofilms, and… read more here.

Keywords: lock solution; edta effective; use; tetrasodium edta ... See more keywords

Is It Possible to Optimize the Elaboration and Preservation of a Vancomycin Catheter Lock Solution?

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Published in 2025 at "Antibiotics"

DOI: 10.3390/antibiotics14060605

Abstract: Background/Objectives: Vancomycin (V) is widely used for catheter lock therapy. However, its ad hoc preparation in pharmacy departments involves discarding most of an intravenous vial and contributes to high workload. We aimed to assess the… read more here.

Keywords: concentration; solution; catheter lock; lock solution ... See more keywords