Measures of tonic and phasic activity of the locus coeruleus—norepinephrine system in children with autism spectrum disorder: An event‐related potential and pupillometry study
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2820
Abstract: A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response… read more here.
Keywords: system; locus coeruleus; norepinephrine system; pupil ... See more keywords
Brain of the tree pangolin (Manis tricuspis). III. The unusual locus coeruleus complex
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24519
Abstract: Here, we used a range of immunohistochemical stains, focussing on tyrosine hydroxylase and dopamine‐β‐hydroxylase, to show that within the pons of tree pangolins clusters of noradrenergic neurons are present. No noradrenergic neurons were observed in… read more here.
Keywords: locus coeruleus; noradrenergic neurons; tree pangolin; coeruleus complex ... See more keywords
Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25474
Abstract: The locus coeruleus (LC) is a small noradrenergic brainstem nucleus that plays a central role in regulating arousal, attention, and performance. In the mammalian brain, individual LC neurons make divergent axonal projections to different brain… read more here.
Keywords: locus coeruleus; area; zebra; corticobasal ganglia ... See more keywords
Characterization of an automated method to segment the human locus coeruleus
Sign Up to like & getrecommendations! Published in 2023 at "Human Brain Mapping"
DOI: 10.1002/hbm.26324
Abstract: Following the development of magnetic resonance imaging (MRI) methods to assay the integrity of catecholamine nuclei, including the locus coeruleus (LC), there has been an effort to develop automated methods that can accurately segment this… read more here.
Keywords: locus coeruleus; manual segmentation; segmentation; characterization automated ... See more keywords
Comparison of Locus Coeruleus Pathology with Nigral and Forebrain Pathology in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2021 at "Movement Disorders"
DOI: 10.1002/mds.28615
Abstract: Pathology in the noradrenergic A6 locus coeruleus has not been compared with more rostral dopaminergic A9 substantia nigra and A10 ventral tegmental area, and cholinergic Ch4 basal nucleus and Ch1/2 septal regions in the same… read more here.
Keywords: coeruleus pathology; comparison locus; pathology; locus coeruleus ... See more keywords
Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28945
Abstract: Parkinson's disease (PD) causes a loss of neuromelanin‐positive, noradrenergic neurons in the locus coeruleus (LC), which has been implicated in nonmotor dysfunction. read more here.
Keywords: coeruleus shows; parkinson disease; locus coeruleus;
Locus Coeruleus Integrity from 7 T MRI Relates to Apathy and Cognition in Parkinsonian Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.29072
Abstract: Neurodegeneration in the locus coeruleus (LC) contributes to neuropsychiatric symptoms in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Spatial precision of LC imaging is improved with ultrahigh field 7 T magnetic resonance imaging. read more here.
Keywords: locus coeruleus; integrity mri; coeruleus integrity; mri relates ... See more keywords
Neuromelanin‐Sensitive Magnetic Resonance Imaging Changes in the Locus Coeruleus/Subcoeruleus Complex in Patients with Typical and Atypical Parkinsonism
Sign Up to like & getrecommendations! Published in 2023 at "Movement Disorders"
DOI: 10.1002/mds.29309
Abstract: The locus coeruleus/subcoeruleus complex (LC/LsC) is a structure comprising melanized noradrenergic neurons. read more here.
Keywords: subcoeruleus complex; locus coeruleus; neuromelanin sensitive; coeruleus subcoeruleus ... See more keywords
Mapping the effects of atomoxetine during response inhibition across cortical territories and the locus coeruleus.
Sign Up to like & getrecommendations! Published in 2021 at "Psychopharmacology"
DOI: 10.1007/s00213-021-05998-2
Abstract: RATIONALE The effects of atomoxetine (ATO) on response inhibition have been typically examined using the stop signal task (SST) which is however confounded by attentional capture. The right inferior frontal cortex (rIFC) has been implicated… read more here.
Keywords: ato; effects atomoxetine; inhibition; locus coeruleus ... See more keywords
Neurochemically distinct circuitry regulates locus coeruleus activity during female social stress depending on coping style
Sign Up to like & getrecommendations! Published in 2019 at "Brain Structure and Function"
DOI: 10.1007/s00429-019-01837-5
Abstract: Stress-related psychiatric diseases are nearly twice as prevalent in women compared to men. We recently showed in male rats that the resident–intruder model of social stress differentially engages stress-related circuitry that regulates norepinephrine-containing neurons of… read more here.
Keywords: social stress; depending coping; locus coeruleus; stress ... See more keywords
Locus Coeruleus Magnetic Resonance Imaging in Neurological Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-020-01087-7
Abstract: Locus coeruleus (LC) is the main noradrenergic nucleus of the brain, and its degeneration is considered to be key in the pathogenesis of neurodegenerative diseases. In the last 15 years,MRI has been used to assess… read more here.
Keywords: resonance imaging; magnetic resonance; coeruleus magnetic; locus coeruleus ... See more keywords