Locus Coeruleus Noradrenergic‐Spinal Projections Contribute to Electroacupuncture‐Mediated Antinociception in Postoperative Pain in Mice
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202501182
Abstract: Postoperative pain remains a significant challenge in healthcare. Electroacupuncture (EA) has gained polarity in helping manage surgical pain and showed beneficial effects on enhancing postoperative analgesia, decreasing opioid requirement. Despite this, the precise mechanisms underlying… read more here.
Keywords: postoperative pain; spinal projections; pain; noradrenergic spinal ... See more keywords
Measures of tonic and phasic activity of the locus coeruleus—norepinephrine system in children with autism spectrum disorder: An event‐related potential and pupillometry study
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2820
Abstract: A growing body of research suggests that locus coeruleus‐norepinephrine (LC‐NE) system may function differently in individuals with autism spectrum disorder (ASD). Understanding the dynamics of both tonic (resting pupil diameter) and phasic (pupil dilation response… read more here.
Keywords: system; locus coeruleus; norepinephrine system; pupil ... See more keywords
Brain of the tree pangolin (Manis tricuspis). III. The unusual locus coeruleus complex
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24519
Abstract: Here, we used a range of immunohistochemical stains, focussing on tyrosine hydroxylase and dopamine‐β‐hydroxylase, to show that within the pons of tree pangolins clusters of noradrenergic neurons are present. No noradrenergic neurons were observed in… read more here.
Keywords: locus coeruleus; noradrenergic neurons; tree pangolin; coeruleus complex ... See more keywords
Divergent projections from locus coeruleus to the corticobasal ganglia system and ventral tegmental area of the adult male zebra finch
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25474
Abstract: The locus coeruleus (LC) is a small noradrenergic brainstem nucleus that plays a central role in regulating arousal, attention, and performance. In the mammalian brain, individual LC neurons make divergent axonal projections to different brain… read more here.
Keywords: locus coeruleus; area; zebra; corticobasal ganglia ... See more keywords
Characterization of an automated method to segment the human locus coeruleus
Sign Up to like & getrecommendations! Published in 2023 at "Human Brain Mapping"
DOI: 10.1002/hbm.26324
Abstract: Following the development of magnetic resonance imaging (MRI) methods to assay the integrity of catecholamine nuclei, including the locus coeruleus (LC), there has been an effort to develop automated methods that can accurately segment this… read more here.
Keywords: locus coeruleus; manual segmentation; segmentation; characterization automated ... See more keywords
The Modulation by the Locus Coeruleus of Recent and Remote Memory Retrieval is Activity‐Dependent
Sign Up to like & getrecommendations! Published in 2025 at "Hippocampus"
DOI: 10.1002/hipo.70004
Abstract: The hippocampus plays a crucial role in acquiring, storing, and retrieving associative experience. Whereas neuromodulatory control of the hippocampus by the locus coeruleus (LC) enhances memory acquisition and consolidation, less is known about its influence… read more here.
Keywords: retrieval; memory; stimulation; memory retrieval ... See more keywords
Comparison of Locus Coeruleus Pathology with Nigral and Forebrain Pathology in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2021 at "Movement Disorders"
DOI: 10.1002/mds.28615
Abstract: Pathology in the noradrenergic A6 locus coeruleus has not been compared with more rostral dopaminergic A9 substantia nigra and A10 ventral tegmental area, and cholinergic Ch4 basal nucleus and Ch1/2 septal regions in the same… read more here.
Keywords: coeruleus pathology; comparison locus; pathology; locus coeruleus ... See more keywords
Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.28945
Abstract: Parkinson's disease (PD) causes a loss of neuromelanin‐positive, noradrenergic neurons in the locus coeruleus (LC), which has been implicated in nonmotor dysfunction. read more here.
Keywords: coeruleus shows; parkinson disease; locus coeruleus;
Locus Coeruleus Integrity from 7 T MRI Relates to Apathy and Cognition in Parkinsonian Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Movement Disorders"
DOI: 10.1002/mds.29072
Abstract: Neurodegeneration in the locus coeruleus (LC) contributes to neuropsychiatric symptoms in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Spatial precision of LC imaging is improved with ultrahigh field 7 T magnetic resonance imaging. read more here.
Keywords: locus coeruleus; integrity mri; coeruleus integrity; mri relates ... See more keywords
Neuromelanin‐Sensitive Magnetic Resonance Imaging Changes in the Locus Coeruleus/Subcoeruleus Complex in Patients with Typical and Atypical Parkinsonism
Sign Up to like & getrecommendations! Published in 2023 at "Movement Disorders"
DOI: 10.1002/mds.29309
Abstract: The locus coeruleus/subcoeruleus complex (LC/LsC) is a structure comprising melanized noradrenergic neurons. read more here.
Keywords: subcoeruleus complex; locus coeruleus; neuromelanin sensitive; coeruleus subcoeruleus ... See more keywords
Early Changes in the Locus Coeruleus in Mild Cognitive Impairment with Lewy Bodies
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders"
DOI: 10.1002/mds.30058
Abstract: Although neuromelanin‐sensitive magnetic resonance imaging (NM‐MRI) has been used to evaluate early neurodegeneration in Parkinson's disease, studies concentrating on the locus coeruleus (LC) in pre‐dementia stages of dementia with Lewy bodies (DLB) are lacking. read more here.
Keywords: changes locus; lewy bodies; coeruleus mild; early changes ... See more keywords