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Comparative and Functional Analyses Reveal Conserved and Variable Regulatory Systems That Control Lasalocid Biosynthesis in Different Streptomyces Species

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Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.03852-22

Abstract: Compared to its elaborated biosynthetic pathway, the regulation of lasalocid biosynthesis remains obscure. Here, we characterize the roles of regulatory genes in lasalocid biosynthetic gene clusters of two distinct Streptomyces species and identify a conserved… read more here.

Keywords: system; biosynthesis; streptomyces species; lodr2 lode ... See more keywords