A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network.
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DOI: 10.1016/j.molcel.2018.08.025
Abstract: Epigenetic control of regulatory networks is only partially understood. Expression of Insulin-like growth factor-II (IGF2) is controlled by genomic imprinting, mediated by silencing of the maternal allele. Loss of imprinting of IGF2 (LOI) is linked… read more here.
Keywords: network; epigenetic control; cell; loi cells ... See more keywords