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Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200081
Abstract: LolO, a 2‐oxoglutarate‐dependent nonheme Fe oxygenase, catalyzes both the hydroxylation of 1‐exo‐acetamidopyrrolizidine (AcAP), a pathway intermediate in the biosynthesis of the loline alkaloids, and the cycloetherification of the resulting alcohol. We have prepared fluorinated AcAP…
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Keywords:
difluoro;
nonheme oxygenase;
acap;
synthesis difluoro ... See more keywords