Stress granule-mediated sequestration of EGR1 mRNAs correlates with lomustine-induced cell death prevention.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of cell science"
DOI: 10.1242/jcs.261825
Abstract: Some chemotherapy drugs modulate the formation of stress granules (SGs), which are RNA-containing cytoplasmic foci contributing to stress response pathways. How SGs mechanistically contribute to pro-survival or pro-apoptotic functions must be better defined. The chemotherapy… read more here.
Keywords: mrnas; stress granule; lomustine induced; stress ... See more keywords
Biochemical, functional, and histopathologic characterization of lomustine-induced liver injury in dogs.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of veterinary research"
DOI: 10.2460/ajvr.81.10.810
Abstract: OBJECTIVE To characterize the biochemical, functional, and histopathologic changes associated with lomustine-induced liver injury in dogs. ANIMALS I0 healthy purpose-bred sexually intact female hounds. PROCEDURES Dogs were randomly assigned to receive lomustine (approx 75 mg/m2,… read more here.
Keywords: liver injury; lomustine induced; biochemical functional;