The role of OleA His285 in orchestration of long‐chain acyl‐coenzyme A substrates
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13004
Abstract: Renewable production of hydrocarbons is being pursued as a petroleum‐independent source of commodity chemicals and replacement for biofuels. The bacterial biosynthesis of long‐chain olefins represents one such platform. The process is initiated by OleA catalyzing… read more here.
Keywords: olea; acyl coenzyme; long chain; role ... See more keywords
Superslippery Long‐Chain Entangled Polydimethylsiloxane Gel with Sustainable Self‐Replenishment
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Engineering Materials"
DOI: 10.1002/adem.202201530
Abstract: Inspired by mucus‐secreting organisms, biomimetic slippery surfaces have been studied in various engineering fields. The liquid‐infused polymer surface (LIPS) has received considerable interest because of its ability to store lubricants inside the polymer itself, facile… read more here.
Keywords: chain entangled; lep gel; long chain; surface ... See more keywords
Metabolic Engineering Strategies for the Enhanced Microalgal Production of Long-Chain Polyunsaturated Fatty Acids (LC-PUFAs).
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology journal"
DOI: 10.1002/biot.201900043
Abstract: Long-chain polyunsaturated fatty acids (LC-PUFAs), largely obtained from fish oil, serve as valuable dietary supplements with many health benefits, especially arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid. In recent years, interest in the sustainable production… read more here.
Keywords: engineering; production; metabolic engineering; fatty acids ... See more keywords
The Pharmacokinetics of Triheptanoin and Its Metabolites in Healthy Subjects and Patients With Long-Chain Fatty Acid Oxidation Disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical pharmacology in drug development"
DOI: 10.1002/cpdd.944
Abstract: Long-chain fatty acid oxidation disorders (LC-FAODs) are a group of life-threatening autosomal recessive disorders caused by defects in nuclear genes encoding mitochondrial enzymes involved in the conversion of dietary long-chain fatty acids into energy. Triheptanoin… read more here.
Keywords: chain; triheptanoin metabolites; fatty acid; long chain ... See more keywords
Interfering with long chain noncoding RNA ANRIL expression reduces heart failure in rats with diabetes by inhibiting myocardial oxidative stress
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29162
Abstract: This study is performed to elucidate whether long‐chain noncoding RNA ANRIL has an effect on diabetes, and further explore the mechanism of ANRIL in diabetes. The rat model of diabetes was established via intraperitoneal injection… read more here.
Keywords: chain noncoding; anril; long chain; expression ... See more keywords
Drug discovery for X‐linked adrenoleukodystrophy: An unbiased screen for compounds that lower very long‐chain fatty acids
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30014
Abstract: X‐linked adrenoleukodystrophy (XALD) is a genetic neurologic disorder with multiple phenotypic presentations and limited therapeutic options. The childhood cerebral phenotype (CCALD), a fatal demyelinating disorder affecting about 35% of patients, and the adult‐onset adrenomyeloneuropathy (AMN),… read more here.
Keywords: c26; linked adrenoleukodystrophy; fatty acids; drug ... See more keywords
Effects of triheptanoin (UX007) in patients with long‐chain fatty acid oxidation disorders: Results from an open‐label, long‐term extension study
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12313
Abstract: Long‐chain fatty acid oxidation disorders (LC‐FAOD) are autosomal recessive conditions that impair conversion of long‐chain fatty acids into energy, leading to significant clinical symptoms. Triheptanoin is a highly purified, 7‐carbon chain triglyceride approved in the… read more here.
Keywords: chain; duration; study; long chain ... See more keywords
Long‐chain fatty acid oxidation and respiratory complex I deficiencies distinguish Barth Syndrome from idiopathic pediatric cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12459
Abstract: Barth syndrome (BTHS) is an X‐linked disorder that results from mutations in the TAFAZZIN gene, which encodes a phospholipid transacylase responsible for generating the mature form of cardiolipin in inner mitochondrial membranes. BTHS patients develop… read more here.
Keywords: oxidation; acid oxidation; barth syndrome; long chain ... See more keywords
Long-Chain Alkyl Epoxides and Glycidyl Ethers: An Underrated Class of Monomers.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202000225
Abstract: Long-chain epoxides and specifically alkyl glycidyl ethers represent a class of highly hydrophobic monomers for anionic ring-opening polymerization (AROP), resulting in apolar aliphatic polyethers. In contrast, poly(ethylene glycol) is known for its high solubility in… read more here.
Keywords: chain; polymerization; amphiphilic polyethers; glycidyl ethers ... See more keywords
Assessment of AMPK-Stimulated Cellular Long-Chain Fatty Acid and Glucose Uptake.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7598-3_22
Abstract: Here we describe an assay for simultaneous measurement of cellular uptake rates of long-chain fatty acids (LCFA) and glucose that can be applied to cells in suspension. The uptake assay includes the use of radiolabeled… read more here.
Keywords: long chain; assessment ampk; lcfa glucose; chain fatty ... See more keywords
Cytotoxicity of novel fluorinated alternatives to long-chain perfluoroalkyl substances to human liver cell line and their binding capacity to human liver fatty acid binding protein
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Toxicology"
DOI: 10.1007/s00204-017-2055-1
Abstract: Although shorter chain homologues and other types of fluorinated chemicals are currently used as alternatives to long-chain perfluoroalkyl substances (PFASs), their safety information remains unclear and urgently needed. Here, the cytotoxicity of several fluorinated alternatives… read more here.
Keywords: long chain; alternatives long; hfpo; acid ... See more keywords