Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19
Sign Up to like & getrecommendations! Published in 2020 at "Nature Immunology"
DOI: 10.1038/s41590-020-00832-x
Abstract: Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity, involved in resistance to selected pathogens and in the regulation of inflammation 1 – 3 . The present study was designed to assess… read more here.
Keywords: long pentraxin; ptx3; covid; pentraxin ptx3 ... See more keywords
Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-89032-7
Abstract: Long pentraxin PTX3, a pattern recognition molecule involved in innate immune responses, is upregulated by pro-inflammatory stimuli, contributors to secondary damage in traumatic brain injury (TBI). We analyzed PTX3 involvement in mice subjected to controlled… read more here.
Keywords: long pentraxin; histopathology; ptx3; pentraxin ptx3 ... See more keywords
Abstract C121: Long Pentraxin-3 modulates bladder cancer progression
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.targ-19-c121
Abstract: Bladder tumors are a diffuse type of cancer with a relatively benign prognosis when treated at early stage/low-grade stages, but with poor outcome in the muscle invasive (MIBC) form or at recurrence. Long Pentraxin-3 (PTX3)… read more here.
Keywords: bladder cancer; long pentraxin; progression; ptx3 ... See more keywords
Long Pentraxin-3 Modulates the Angiogenic Activity of Fibroblast Growth Factor-2
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02327
Abstract: Angiogenesis, the process of new blood vessel formation from pre-existing ones, plays a key role in various physiological and pathological conditions. Alteration of the angiogenic balance, consequent to the deranged production of angiogenic growth factors… read more here.
Keywords: growth factor; long pentraxin; growth; fibroblast growth ... See more keywords
The Long Pentraxin PTX3 Is of Major Importance Among Acute Phase Proteins in Chickens
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00124
Abstract: The expression level of acute phase proteins (APPs) mirrors the health status of an individual. In human medicine, C-reactive protein (CRP), and other members of the pentraxin family are of significant relevance for assessing disease… read more here.
Keywords: acute phase; long pentraxin; ptx3 major; pentraxin ptx3 ... See more keywords
Functional Genetic Variant of Long Pentraxin 3 Gene Is Associated With Clinical Aspects of Oral Cancer in Male Patients
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.00581
Abstract: Long pentraxin 3 (PTX3) is produced by various cell types and is correlated with tumor progression in various tumor types. However, the clinical significance of PTX3 polymorphisms in oral cancer and their correlation with the… read more here.
Keywords: long pentraxin; oral cancer; variant; cancer ... See more keywords
β-Galactosylceramidase Deficiency Causes Upregulation of Long Pentraxin-3 in the Central Nervous System of Krabbe Patients and Twitcher Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169436
Abstract: Globoid cell leukodystrophy (GLD), or Krabbe disease, is a neurodegenerative sphingolipidosis caused by genetic deficiency of lysosomal β-galactosylceramidase (GALC), characterized by neuroinflammation and demyelination of the central (CNS) and peripheral nervous system. The acute phase… read more here.
Keywords: patients twitcher; ptx3; krabbe patients; long pentraxin ... See more keywords
Perspectives on long pentraxin 3 and rheumatoid arthritis: several potential breakthrough points relying on study foundation of the past
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.54787
Abstract: Rheumatoid arthritis (RA) is a systemic chronic autoimmune inflammatory disease which is mainly characterized by synovitis and results in a severe burden for both the individual and society. To date, the underlying mechanisms of RA… read more here.
Keywords: long pentraxin; perspectives long; pentraxin rheumatoid; rheumatoid arthritis ... See more keywords