Bacterial reverse transcriptase synthesizes long poly-A-rich cDNA for antiphage defense.
Sign Up to like & getrecommendations! Published in 2025 at "Science"
DOI: 10.1126/science.ads4639
Abstract: Prokaryotic defense-associated reverse transcriptases (DRTs) were recently identified with antiviral functions; however, their functional mechanisms remain largely unexplored. Here we show that DRT9 forms a hexameric complex with its upstream non-coding RNA (ncRNA) to mediate… read more here.
Keywords: antiphage defense; long poly; bacterial reverse; defense ... See more keywords