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Published in 2022 at "eLife"
DOI: 10.1101/2021.12.17.473103
Abstract: MicroRNAs (miR) are important posttranscriptional regulators and exhibit a high potential to be utilized in diagnosis and therapy. However, our insufficient knowledge of the miR-mediated gene regulation in human skin wound healing severely hinders the…
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Keywords:
wound;
small long;
rna omics;
long rna ... See more keywords
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Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-5686
Abstract: Growing research in oncology implicates exosomes in cell-to-cell communication and various cancer patho-physiologies. Vesicle-mediated signaling is thought to occur via both protein and RNA transport. However, there is a fundamental lack of understanding regarding the…
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Keywords:
long rna;
plasma;
rna;
coverage ... See more keywords
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2
Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-260
Abstract: HEK293 cells are used extensively in cancer research, with more than 4800 articles between 2017 and 2022 (PubMed search “cancer[MeSH Major Topic] and hek293”). Studies involving transfection to overexpress, knock down, or modify proteins in…
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Keywords:
rna dna;
hek293 cells;
commercial sources;
long rna ... See more keywords
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Published in 2022 at "BMC Biology"
DOI: 10.1186/s12915-022-01277-4
Abstract: Background Extracellular vesicles (EVs) are released by nearly every cell type and have attracted much attention for their ability to transfer protein and diverse RNA species from donor to recipient cells. Much attention has been…
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Keywords:
long rna;
extracellular vesicles;
lncrna transcripts;
transcriptome ... See more keywords
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Published in 2019 at "Clinical chemistry"
DOI: 10.1373/clinchem.2018.301291
Abstract: BACKGROUND Extracellular vesicles (EVs) contain a rich cargo of different RNA species with specialized functions and clinical applications. However, the landscape and characteristics of extracellular vesicle long RNA (exLR) in human blood remain largely unknown.…
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Keywords:
extracellular vesicles;
long rna;
diagnosis;
human blood ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020968
Abstract: As part of a complex network of genome control, long regulatory RNAs exert significant influences on chromatin dynamics. Understanding how this occurs could illuminate new avenues for disease treatment and lead to new hypotheses that…
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Keywords:
long rna;
chromatin regulation;
fission yeast;
regulation ... See more keywords